Gao, Tianyan

PHLPP: A phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth

Gao, T., Furnari, F., & Newton, A. C. (2005) · Molecular Cell

PI3K/AKT/mTOR signaling in cancerProtein Tyrosine Phosphatases

Cited by 906

PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms

Brognard, J., Sierecki, E., Gao, T., & Newton, A. C. (2007) · Molecular Cell

PI3K/AKT/mTOR signaling in cancerProtein Tyrosine Phosphatases

Cited by 591

Increased expression of fatty acid synthase provides a survival advantage to colorectal cancer cells via upregulation of cellular respiration

Zaytseva, Y. Y., Harris, J. W., Mitov, M. I., Kim, J. T., Butterfield, D. A., Lee, E. Y., Weiss, H. L., Gao, T., & Evers, B. M. (2015) · Oncotarget

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

Cited by 153

Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer

Zaytseva, Y. Y., Rychahou, P. G., Le, A.-T., Scott, T. L., Flight, R. M., Kim, J. T., Harris, J., Liu, J., Wang, C., Morris, A. J., et al. (2018) · Oncotarget

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

Cited by 123

Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer

Zaytseva, Y. Y., Elliott, V. A., Rychahou, P., Mustain, W. C., Kim, J. T., Valentino, J., Gao, T., O’Connor, K. L., Neltner, J. M., Lee, E. Y., et al. (2014) · Carcinogenesis

Cancer, Lipids, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 104