Sokol, Harry

The mutational constraint spectrum quantified from variation in 141,456 humans

Karczewski, K. J., Francioli, L. C., Tiao, G., Cummings, B. B., Alföldi, J., Wang, Q., Collins, R. L., Laricchia, K. M., Ganna, A., Birnbaum, D. P., et al. (2020) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

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Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., Blugeon, S., Bridonneau, C., Furet, J.-P., Corthier, G., et al. (2008) · Proceedings of the National Academy of Sciences

Gut microbiota and healthInflammatory Bowel Disease

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Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease

Agus, A., Planchais, J., & Sokol, H. (2018) · Cell Host & Microbe

Gut microbiota and healthTryptophan and brain disorders

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Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

Morgan, X. C., Tickle, T. L., Sokol, H., Gevers, D., Devaney, K. L., Ward, D. V., Reyes, J. A., Shah, S. A., LeLeiko, N., Snapper, S. B., et al. (2012) · Genome Biology

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Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

Lavelle, A., & Sokol, H. (2020) · Nature Reviews Gastroenterology & Hepatology

Gut microbiota and healthInflammatory Bowel Disease

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The Firmicutes/Bacteroidetes ratio of the human microbiota changes with age

Mariat, D., Firmesse, O., Levenez, F., Guimarăes, V., Sokol, H., Doré, J., Corthier, G., & Furet, J.-P. (2009) · BMC Microbiology

Gut microbiota and healthInfant Nutrition and Health

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A genomic mutational constraint map using variation in 76,156 human genomes

Chen, S., Francioli, L. C., Goodrich, J. K., Collins, R. L., Kanai, M., Wang, Q., Alföldi, J., Watts, N. A., Vittal, C., Gauthier, L. D., et al. (2024) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

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CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Lamas, B., Richard, M. L., Leducq, V., Pham, H.-P., Michel, M.-L., Da Costa, G., Bridonneau, C., Jegou, S., Hoffmann, T. W., Natividad, J. M., et al. (2016) · Nature Medicine

Gut microbiota and healthInflammatory Bowel Disease

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Gut microbiota-derived metabolites as central regulators in metabolic disorders

Agus, A., Clément, K., & Sokol, H. (2021) · Gut

Gut microbiota and healthMetabolomics and Mass Spectrometry Studies

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Low counts of Faecalibacterium prausnitzii in colitis microbiota

Sokol, H., Seksik, P., Furet, J. P., Firmesse, O., Nion-Larmurier, I., Beaugerie, L., Cosnes, J., Corthier, G., Marteau, P., & Doré, J. (2009) · Inflammatory Bowel Diseases

Gut microbiota and healthInflammatory Bowel Disease

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European consensus conference on faecal microbiota transplantation in clinical practice

Cammarota, G., Ianiro, G., Tilg, H., Rajilić-Stojanović, M., Kump, P., Satokari, R., Sokol, H., Arkkila, P., Pintus, C., Hart, A., et al. (2017) · Gut

Clostridium difficile and Clostridium perfringens researchGut microbiota and health

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A structural variation reference for medical and population genetics

Collins, R. L., Brand, H., Karczewski, K. J., Zhao, X., Alföldi, J., Francioli, L. C., Khera, A. V., Lowther, C., Gauthier, L. D., Wang, H., et al. (2020) · Nature

Genomic variations and chromosomal abnormalitiesGenomics and Rare Diseases

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Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

Duboc, H., Rajca, S., Rainteau, D., Benarous, D., Maubert, M.-A., Quervain, E., Thomas, G., Barbu, V., Humbert, L., Despras, G., et al. (2013) · Gut

Gut microbiota and healthInflammatory Bowel Disease

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Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

Daillère, R., Vétizou, M., Waldschmitt, N., Yamazaki, T., Isnard, C., Poirier-Colame, V., Duong, C. P. M., Flament, C., Lepage, P., Roberti, M. P., et al. (2016) · Immunity

Cancer Immunotherapy and BiomarkersGut microbiota and health

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Impaired aryl hydrocarbon receptor ligand production by the gut microbiota is a key factor in metabolic syndrome

Natividad, J. M., Agus, A., Planchais, J., Lamas, B., Jarry, A. C., Martin, R., Michel, M.-L., Chong-Nguyen, C., Roussel, R., Straube, M., et al. (2018) · Cell Metabolism

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

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Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

Federici, S., Kredo-Russo, S., Valdés-Mas, R., Kviatcovsky, D., Weinstock, E., Matiuhin, Y., Silberberg, Y., Atarashi, K., Furuichi, M., Oka, A., et al. (2022) · Cell

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International consensus conference on stool banking for faecal microbiota transplantation in clinical practice

Cammarota, G., Ianiro, G., Kelly, C. R., Mullish, B. H., Allegretti, J. R., Kassam, Z., Putignani, L., Fischer, M., Keller, J. J., Costello, S. P., et al. (2019) · Gut

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Functional Characterization of Novel Faecalibacterium prausnitzii Strains Isolated from Healthy Volunteers: A Step Forward in the Use of F. prausnitzii as a Next-Generation Probiotic

Martín, R., Miquel, S., Benevides, L., Bridonneau, C., Robert, V., Hudault, S., Chain, F., Berteau, O., Azevedo, V., Chatel, J. M., et al. (2017) · Frontiers in Microbiology

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Fecal microbiota transplantation to maintain remission in Crohn's disease: A pilot randomized controlled study

Saint-Antoine IBD Network, Sokol, H., Landman, C., Seksik, P., Berard, L., Montil, M., Nion-Larmurier, I., Bourrier, A., Le Gall, G., Lalande, V., et al. (2020) · Microbiome

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Key determinants of success in fecal microbiota transplantation: From microbiome to clinic

Porcari, S., Benech, N., Valles-Colomer, M., Segata, N., Gasbarrini, A., Cammarota, G., Sokol, H., & Ianiro, G. (2023) · Cell Host & Microbe

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Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model

Martín, R., Miquel, S., Chain, F., Natividad, J. M., Jury, J., Lu, J., Sokol, H., Theodorou, V., Bercik, P., Verdu, E. F., et al. (2015) · BMC Microbiology

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The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models

Martín, R., Chain, F., Miquel, S., Lu, J., Gratadoux, J.-J., Sokol, H., Verdu, E. F., Bercik, P., Bermúdez-Humarán, L. G., & Langella, P. (2014) · Inflammatory Bowel Diseases

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Increase in fecal primary bile acids and dysbiosis in patients with diarrhea‐predominant irritable bowel syndrome

Duboc, H., Rainteau, D., Rajca, S., Humbert, L., Farabos, D., Maubert, M., Grondin, V., Jouet, P., Bouhassira, D., Seksik, P., et al. (2012) · Neurogastroenterology & Motility

Gastrointestinal motility and disordersGut microbiota and health

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Probiotic Strain Lactobacillus casei BL23 Prevents Colitis‐Associated Colorectal Cancer

Jacouton, E., Chain, F., Sokol, H., Langella, P., & Bermúdez-Humarán, L. G. (2017) · Frontiers in Immunology

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