Falkenberg, Maria

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Trifunovic, A., Wredenberg, A., Falkenberg, M., Spelbrink, J. N., Rovio, A. T., Bruder, C. E., Bohlooly-Y, M., Gidlöf, S., Oldfors, A., Wibom, R., et al. (2004) · Nature

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 2,734

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA

Falkenberg, M., Gaspari, M., Rantanen, A., Trifunovic, A., Larsson, N.-G., & Gustafsson, C. M. (2002) · Nature Genetics

Mitochondrial Function and PathologyGenomics and Chromatin Dynamics

Cited by 598

TWINKLE Has 5' −>3' DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein

Korhonen, J. A., Gaspari, M., & Falkenberg, M. (2003) · Journal of Biological Chemistry

DNA Repair MechanismsMitochondrial Function and Pathology

Cited by 298

TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication

Milenkovic, D., Matic, S., Kuhl, I., Ruzzenente, B., Freyer, C., Jemt, E., Park, C. B., Falkenberg, M., & Larsson, N.-G. (2013) · Human Molecular Genetics

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 173

Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element

Jemt, E., Persson, Ö., Shi, Y., Mehmedovic, M., Uhler, J. P., Dávila López, M., Freyer, C., Gustafsson, C. M., Samuelsson, T., & Falkenberg, M. (2015) · Nucleic Acids Research

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 121

Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization

Zhu, X., Xie, X., Das, H., Tan, B. G., Shi, Y., Al-Behadili, A., Peter, B., Motori, E., Valenzuela, S., Posse, V., et al. (2022) · Cell

Mitochondrial Function and PathologyGenomics and Chromatin Dynamics

Cited by 69

Defective mitochondrial protease LonP1 can cause classical mitochondrial disease

Peter, B., Waddington, C. L., Oláhová, M., Sommerville, E. W., Hopton, S., Pyle, A., Champion, M., Ohlson, M., Siibak, T., Chrzanowska-Lightowlers, Z. M. A., et al. (2018) · Human Molecular Genetics

Mitochondrial Function and PathologyMetabolism and Genetic Disorders

Cited by 66

The accessory subunit B of DNA polymerase is required for mitochondrial replisome function

Farge, G., Pham, X. H., Holmlund, T., Khorostov, I., & Falkenberg, M. (2007) · Nucleic Acids Research

Mitochondrial Function and PathologyDNA Repair Mechanisms

Cited by 62