Muqit, Miratul M. K.

Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1

Valente, E. M., Abou-Sleiman, P. M., Caputo, V., Muqit, M. M. K., Harvey, K., Gispert, S., Ali, Z., Del Turco, D., Bentivoglio, A. R., Healy, D. G., et al. (2004) · Science

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 3,481

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

Kondapalli, C., Kazlauskaite, A., Zhang, N., Woodroof, H. I., Campbell, D. G., Gourlay, R., Burchell, L., Walden, H., Macartney, T. J., Deak, M., et al. (2012) · Open Biology

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 940

Expanding insights of mitochondrial dysfunction in Parkinson's disease

Abou-Sleiman, P. M., Muqit, M. M. K., & Wood, N. W. (2006) · Nature Reviews Neuroscience

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

Cited by 869

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

Kazlauskaite, A., Kondapalli, C., Gourlay, R., Campbell, D. G., Ritorto, M. S., Hofmann, K., Alessi, D. R., Knebel, A., Trost, M., & Muqit, M. M. K. (2014) · Biochemical Journal

Parkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathways

Cited by 806

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

McWilliams, T. G., Prescott, A. R., Montava-Garriga, L., Ball, G., Singh, F., Barini, E., Muqit, M. M. K., Brooks, S. P., & Ganley, I. G. (2018) · Cell Metabolism

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 591

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice

Schulz, J. B., Matthews, R. T., Muqit, M. M. K., Browne, S. E., & Beal, M. F. (1995) · Journal of Neurochemistry

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 417

Mapping of a N-terminal α-helix domain required for human PINK1 stabilization, Serine228 autophosphorylation and activation in cells

Kakade, P., Ojha, H., Raimi, O. G., Shaw, A., Waddell, A. D., Ault, J. R., Burel, S., Brockmann, K., Kumar, A., Ahangar, M. S., et al. (2022) · Open Biology

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 42

Mechanism of human PINK1 activation at the TOM complex in a reconstituted system

Raimi, O. G., Ojha, H., Ehses, K., Dederer, V., Lange, S. M., Rivera, C. P., Deegan, T. D., Chen, Y., Wightman, M., Toth, R., et al. (2023) · Science Advances

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and Pathology

Cited by 39

CURTAIN – A Unique Web-based tool for exploration and sharing of MS-based proteomics data

Phung, T. K., Berndsen, K., Phan, T. L. C. H. B., Muqit, M. M. K., Alessi, D. R., & Nirujogi, R. S. (2023) · Proceedings of the National Academy of Sciences

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 18

CURTAIN—A unique web-based tool for exploration and sharing of MS-based proteomics data

Phung, T. K., Berndsen, K., Shastry, R., Phan, T. L. C. H. B., Muqit, M. M. K., Alessi, D. R., & Nirujogi, R. S. (2024) · Proceedings of the National Academy of Sciences

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 18

A Functional Genetic Atlas of Parkin Resolves Variants of Uncertain Significance and Predicts Parkinson’s Disease Age at Onset

Aslanzadeh, V., Glendinning, S., Sari, Y., Clarke, M., Rodger, C. J., Lin, X., Lenka, D. R., Richardson, L., Liang, J. R., Kleinz, T., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Parkinson's Disease Mechanisms and TreatmentsGenomics and Rare Diseases

Cited by 1