Shimura, Hideki

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Shimura, H., Hattori, N., Kubo, S.-I., Mizuno, Y., Asakawa, S., Minoshima, S., Shimizu, N., Iwai, K., Chiba, T., Tanaka, K., et al. (2000) · Nature Genetics

Parkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathways

Cited by 2,024

Ubiquitination of a new form of α-synuclein by parkin from human brain: implications for Parkinson's disease

Shimura, H., Schlossmacher, M. G., Hattori, N., Frosch, M. P., Trockenbacher, A., Schneider, R., Mizuno, Y., Kosik, K. S., & Selkoe, D. J. (2001) · Science

Parkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathways

Cited by 1,053

Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocyte progenitors and enhances regeneration of ischemic white matter lesions in the adult mammalian brain

Miyamoto, N., Tanaka, R., Shimura, H., Watanabe, T., Mori, H., Onodera, M., Mochizuki, H., Hattori, N., & Urabe, T. (2010) · Journal of Cerebral Blood Flow & Metabolism

Neurological Disease Mechanisms and TreatmentsNeurogenesis and neuroplasticity mechanisms

Cited by 86

Exendin-4 Inhibits Matrix Metalloproteinase-9 Activation and Reduces Infarct Growth After Focal Cerebral Ischemia in Hyperglycemic Mice

Kuroki, T., Tanaka, R., Shimada, Y., Yamashiro, K., Ueno, Y., Shimura, H., Urabe, T., & Hattori, N. (2016) · Stroke

Acute Ischemic Stroke ManagementNeuroprotection in Cerebral Ischemia

Cited by 60

New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers

Ochiishi, T., Kaku, M., Kiyosue, K., Doi, M., Urabe, T., Hattori, N., Shimura, H., & Ebihara, T. (2019) · Scientific Reports

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 34

Anhedonia and its correlation with clinical aspects in Parkinson’s disease

Nagayama, H., Maeda, T., Uchiyama, T., Hashimoto, M., Nomoto, N., Kano, O., Takahashi, T., Terashi, H., Hamada, S., Hasegawa, T., et al. (2017) · Journal of the Neurological Sciences

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 33