Avramescu, Radu G.

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression

Veit, G., Avramescu, R. G., Perdomo, D., Phuan, P.-W., Bagdany, M., Apaja, P. M., Borot, F., Szollosi, D., Wu, Y.-S., Finkbeiner, W. E., et al. (2014) · Science Translational Medicine

Cystic Fibrosis Research AdvancesIon Transport and Channel Regulation

Cited by 287

Structure-guided combination therapy to potently improve the function of mutant CFTRs

Veit, G., Xu, H., Dreano, E., Avramescu, R. G., Bagdany, M., Beitel, L. K., Roldan, A., Hancock, M. A., Lay, C., Li, W., et al. (2018) · Nature Medicine

Cystic Fibrosis Research AdvancesGenetic and Kidney Cyst Diseases

Cited by 134

Mutation-specific downregulation of CFTR2 variants by gating potentiators

Avramescu, R. G., Kai, Y., Xu, H., Bidaud-Meynard, A., Schnúr, A., Frenkiel, S., Matouk, E., Veit, G., & Lukacs, G. L. (2017) · Human Molecular Genetics

Cystic Fibrosis Research AdvancesInhalation and Respiratory Drug Delivery

Cited by 43

Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice

Reynolds, L. M., Hernandez, G., MacGowan, D., Popescu, C., Nouel, D., Cuesta, S., Burke, S., Savell, K. E., Zhao, J., Restrepo-Lozano, J. M., et al. (2023) · Nature Communications

Neurotransmitter Receptor Influence on BehaviorAxon Guidance and Neuronal Signaling

Cited by 30

The scheduling of adolescence with Netrin-1 and UNC5C

Hoops, D., Kyne, R., Salameh, S., MacGowan, D., Avramescu, R. G., Ewing, E., He, A. T., Orsini, T., Durand, A., Popescu, C., et al. (2024) · eLife

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

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