Backx, Peter H.

Angiotensin-converting enzyme 2 is an essential regulator of heart function

Crackower, M. A., Sarao, R., Oudit, G. Y., Yagil, C., Kozieradzki, I., Scanga, S. E., Oliveira-dos-Santos, A. J., da Costa, J., Zhang, L., Pei, Y., et al. (2002) · Nature

Renin-Angiotensin System StudiesEicosanoids and Hypertension Pharmacology

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Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes

Nunes, S. S., Miklas, J. W., Liu, J., Aschar-Sobbi, R., Xiao, Y., Zhang, B., Jiang, J., Massé, S., Gagliardi, M., Hsieh, A., et al. (2013) · Nature Methods

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

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A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling

Zhao, Y., Rafatian, N., Feric, N. T., Cox, B. J., Aschar-Sobbi, R., Wang, E. Y., Aggarwal, P., Zhang, B., Conant, G., Ronaldson-Bouchard, K., et al. (2019) · Cell

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 610

GLP-1 receptor activation and epac2 link atrial natriuretic peptide secretion to control of blood pressure

Kim, M., Platt, M. J., Shibasaki, T., Quaggin, S. E., Backx, P. H., Seino, S., Simpson, J. A., & Drucker, D. J. (2013) · Nature Medicine

Diabetes Treatment and ManagementBlood Pressure and Hypertension Studies

Cited by 514

L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy

Oudit, G. Y., Sun, H., Trivieri, M. G., Koch, S. E., Dawood, F., Ackerley, C., Yazdanpanah, M., Wilson, G. J., Schwartz, A., Liu, P. P., et al. (2003) · Nature Medicine

Iron Metabolism and DisordersCardiac electrophysiology and arrhythmias

Cited by 480

Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker

Protze, S. I., Liu, J., Nussinovitch, U., Ohana, L., Backx, P. H., Gepstein, L., & Keller, G. M. (2017) · Nature Biotechnology

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 366

Circadian rhythm disorganization produces profound cardiovascular and renal disease in hamsters

Martino, T. A., Oudit, G. Y., Herzenberg, A. M., Tata, N., Koletar, M. M., Kabir, G. M., Belsham, D. D., Backx, P. H., Ralph, M. R., & Sole, M. J. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 317

Disturbed diurnal rhythm alters gene expression and exacerbates cardiovascular disease with rescue by resynchronization

Martino, T. A., Tata, N., Belsham, D. D., Chalmers, J., Straume, M., Lee, P., Pribiag, H., Khaper, N., Liu, P. P., Dawood, F., et al. (2007) · Hypertension

Circadian rhythm and melatoninCardiac electrophysiology and arrhythmias

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Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFα

Aschar-Sobbi, R., Izaddoustdar, F., Korogyi, A. S., Wang, Q., Farman, G. P., Yang, F., Yang, W., Dorian, D., Simpson, J. A., Tuomi, J. M., et al. (2015) · Nature Communications

Cardiovascular Effects of ExerciseCardiac electrophysiology and arrhythmias

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The Primary Benefits of Angiotensin-Converting Enzyme Inhibition on Cardiac Remodeling Occur During Sleep Time in Murine Pressure Overload Hypertrophy

Martino, T. A., Tata, N., Simpson, J. A., Vanderlaan, R., Dawood, F., Kabir, M. G., Khaper, N., Cifelli, C., Podobed, P., Liu, P. P., et al. (2011) · Journal of the American College of Cardiology

Renin-Angiotensin System StudiesCardiac Fibrosis and Remodeling

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