Sauve, Anthony A.

The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

Cantó, C., Houtkooper, R. H., Pirinen, E., Youn, D. Y., Oosterveer, M. H., Cen, Y., Fernandez-Marcos, P. J., Yamamoto, H., Andreux, P. A., Cettour-Rose, P., et al. (2012) · Cell Metabolism

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 1,238

Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival

Yang, H., Yang, T., Baur, J. A., Perez, E., Matsui, T., Carmona, J. J., Lamming, D. W., Souza-Pinto, N. C., Bohr, V. A., Rosenzweig, A., et al. (2007) · Cell

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 950

PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

Bai, P., Cantó, C., Oudart, H., Brunyánszki, A., Cen, Y., Thomas, C., Yamamoto, H., Huber, A., Kiss, B., Houtkooper, R. H., et al. (2011) · Cell Metabolism

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 837

The biochemistry of sirtuins

Sauve, A. A., Wolberger, C., Schramm, V. L., & Boeke, J. D. (2006) · Annual Review of Biochemistry

Sirtuins and Resveratrol in MedicineHistone Deacetylase Inhibitors Research

Cited by 763

Neuronal SIRT1 Activation as a Novel Mechanism Underlying the Prevention of Alzheimer Disease Amyloid Neuropathology by Calorie Restriction

Qin, W., Yang, T., Ho, L., Zhao, Z., Wang, J., Chen, L., Zhao, W., Thiyagarajan, M., MacGrogan, D., Rodgers, J. T., et al. (2006) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsSirtuins and Resveratrol in Medicine

Cited by 626

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

Gariani, K., Menzies, K. J., Ryu, D., Wegner, C. J., Wang, X., Ropelle, E. R., Moullan, N., Zhang, H., Perino, A., Lemos, V., et al. (2016) · Hepatology

Sirtuins and Resveratrol in MedicineLiver Disease Diagnosis and Treatment

Cited by 368

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

Gong, B., Pan, Y., Vempati, P., Zhao, W., Knable, L., Ho, L., Wang, J., Sastre, M., Ono, K., Sauve, A. A., et al. (2013) · Neurobiology of Aging

Alzheimer's disease research and treatmentsSirtuins and Resveratrol in Medicine

Cited by 345

NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

Cerutti, R., Pirinen, E., Lamperti, C., Marchet, S., Sauve, A. A., Li, W., Leoni, V., Schon, E. A., Dantzer, F., Auwerx, J., et al. (2014) · Cell Metabolism

Sirtuins and Resveratrol in MedicineMitochondrial Function and Pathology

Cited by 343

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

Mitchell, S. J., Bernier, M., Aon, M. A., Cortassa, S., Kim, E. Y., Fang, E. F., Palacios, H. H., Ali, A., Navas-Enamorado, I., Di Francesco, A., et al. (2018) · Cell Metabolism

Sirtuins and Resveratrol in MedicineGenetics, Aging, and Longevity in Model Organisms

Cited by 338

Activation of SIRT3 by the NAD(+) precursor nicotinamide riboside protects from noise-induced hearing loss

Brown, K. D., Maqsood, S., Huang, J.-Y., Pan, Y., Harkcom, W., Li, W., Sauve, A., Verdin, E., & Jaffrey, S. R. (2014) · Cell Metabolism

Sirtuins and Resveratrol in MedicineHearing, Cochlea, Tinnitus, Genetics

Cited by 277

NAD + repletion improves muscle function in muscular dystrophy and counters global PARylation

Ryu, D., Zhang, H., Ropelle, E. R., Sorrentino, V., Mázala, D. A. G., Mouchiroud, L., Marshall, P. L., Campbell, M. D., Ali, A. S., Knowels, G. M., et al. (2016) · Science Translational Medicine

Sirtuins and Resveratrol in MedicineMuscle Physiology and Disorders

Cited by 256

Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle

Pirinen, E., Cantó, C., Jo, Y. S., Morato, L., Zhang, H., Menzies, K. J., Williams, E. G., Mouchiroud, L., Moullan, N., Hagberg, C., et al. (2014) · Cell Metabolism

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

Cited by 254

Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes

Cantó, C., Sauve, A. A., & Bai, P. (2013) · Molecular Aspects of Medicine

Sirtuins and Resveratrol in MedicinePARP inhibition in cancer therapy

Cited by 246

Fasting and refeeding differentially regulate NLRP3 inflammasome activation in human subjects

Traba, J., Kwarteng-Siaw, M., Okoli, T. C., Li, J., Huffstutler, R. D., Bray, A., Waclawiw, M. A., Han, K., Pelletier, M., Sauve, A. A., et al. (2015) · Journal of Clinical Investigation

Inflammasome and immune disordersSirtuins and Resveratrol in Medicine

Cited by 180

Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets

Apontes, P., Liu, Z., Su, K., Benard, O., Youn, D. Y., Li, X., Li, W., Mirza, R. H., Bastie, C. C., Jelicks, L. A., et al. (2014) · Diabetes

Mangiferin and Mango ExtractsNatural Antidiabetic Agents Studies

Cited by 69

Dual mode action of mangiferin in mouse liver under high fat diet

Lim, J., Liu, Z., Apontes, P., Feng, D., Pessin, J. E., Sauve, A. A., Angeletti, R. H., & Chi, Y. (2014) · PLoS ONE

Mangiferin and Mango ExtractsNatural Antidiabetic Agents Studies

Cited by 64