Look, A. Thomas

Acute lymphoblastic leukaemia

Pui, C.-H., Robison, L. L., & Look, A. T. (2008) · The Lancet

Acute Lymphoblastic Leukemia researchLymphoma Diagnosis and Treatment

Cited by 1,564

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

Niethammer, P., Grabher, C., Look, A. T., & Mitchison, T. J. (2009) · Nature

Zebrafish Biomedical Research ApplicationsWound Healing and Treatments

Cited by 1,541

Activating mutations in ALK provide a therapeutic target in neuroblastoma

George, R. E., Sanda, T., Hanna, M., Fröhling, S., II, W. L., Zhang, J., Ahn, Y., Zhou, W., London, W. B., McGrady, P., et al. (2008) · Nature

Neuroblastoma Research and TreatmentsNeurofibromatosis and Schwannoma Cases

Cited by 893

An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

Mansour, M. R., Abraham, B. J., Anders, L., Berezovskaya, A., Gutierrez, A., Durbin, A. D., Etchin, J., Lawton, L., Sallan, S. E., Silverman, L. B., et al. (2014) · Science

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 801

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

Maser, R. S., Choudhury, B., Campbell, P. J., Feng, B., Wong, K.-K., Protopopov, A., O’Neil, J., Gutierrez, A., Ivanova, E., Perna, I., et al. (2007) · Nature

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 377

The Requirement for Cyclin D Function in Tumor Maintenance

Choi, Y. J., Li, X., Hydbring, P., Sanda, T., Stefano, J., Christie, A. L., Signoretti, S., Look, A. T., Kung, A. L., von Boehmer, H., et al. (2012) · Cancer Cell

Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

Cited by 342

Bone-Marrow Transplantation in a Patient with Sickle-Cell Anemia

Johnson, F. L., Look, A. T., Gockerman, J., Ruggiero, M. R., Dalla-Pozza, L., & Billings, F. T. (1984) · New England Journal of Medicine

Hemoglobinopathies and Related DisordersHematopoietic Stem Cell Transplantation

Cited by 321

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

Townsend, E. C., Murakami, M. A., Christodoulou, A., Christie, A. L., Köster, J., DeSouza, T. A., Morgan, E. A., Kallgren, S. P., Liu, H., Wu, S.-C., et al. (2016) · Cancer Cell

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 295

Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia

Gutierrez, A., Pan, L., Groen, R. W. J., Baleydier, F., Kentsis, A., Marineau, J., Grebliunaite, R., Kozakewich, E., Reed, C., Pflumio, F., et al. (2014) · Journal of Clinical Investigation

Acute Lymphoblastic Leukemia researchProtein Tyrosine Phosphatases

Cited by 220

Identification of a Region Which Directs the Monocytic Activity of the Colony-Stimulating Factor 1 (Macrophage Colony-Stimulating Factor) Receptor Promoter and Binds PEBP2/CBF (AML1)

Zhang, D.-E., Fujioka, K.-I., Hetherington, C. J., Shapiro, L. H., Chen, H.-M., Look, A. T., & Tenen, D. G. (1994) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 199

Zebrafish foxd3 is selectively required for neural crest specification, migration and survival

Stewart, R. A., Arduini, B. L., Berghmans, S., George, R. E., Kanki, J. P., Henion, P. D., & Look, A. T. (2006) · Developmental Biology

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 180

The public repository of xenografts enables discovery and randomized phase II-like trials in mice

Townsend, E. C., Murakami, M. A., Christodoulou, A., Christie, A. L., Köster, J., DeSouza, T. A., Morgan, E. A., Kallgren, S. P., Liu, H., Wu, S.-C., et al. (2016) · Cancer Cell

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia Research

Cited by 80

Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X

Liu, Y., Li, C., Shen, S., Chen, X., Szlachta, K., Edmonson, M. N., Shao, Y., Ma, X., Hyle, J., Wright, S., et al. (2020) · Nature Genetics

Cancer Genomics and DiagnosticsGenomics and Chromatin Dynamics

Cited by 64

Aberrant AKT activation drives well-differentiated liposarcoma

Gutierrez, A., Snyder, E. L., Marino-Enriquez, A., Zhang, Y.-X., Sioletic, S., Kozakewich, E., Grebliunaite, R., Ou, W.-B., Sicinska, E., Raut, C. P., et al. (2011) · Proceedings of the National Academy of Sciences

Sarcoma Diagnosis and TreatmentPI3K/AKT/mTOR signaling in cancer

Cited by 58