Chiang, Claire Y

Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase

Dhekne, H. S., Tonelli, F., Yeshaw, W. M., Chiang, C. Y., Limouse, C., Jaimon, E., Purlyte, E., Alessi, D. R., & Pfeffer, S. R. (2023) · eLife

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

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A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation

Vides, E. G., Adhikari, A., Chiang, C. Y., Lis, P., Purlyte, E., Limouse, C., Shumate, J. L., Spínola-Lasso, E., Dhekne, H. S., Alessi, D. R., et al. (2022) · eLife

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 63

A Feed-forward Pathway Drives LRRK2 kinase Membrane Recruitment and Activation

Vides, E. G., Adhikari, A., Chiang, C. Y., Lis, P., Purlyte, E., Limouse, C., Shumate, J. L., Spínola-Lasso, E., Dhekne, H. S., Alessi, D. R., et al. (2022) · eLife

Parkinson's Disease Mechanisms and TreatmentsCellular transport and secretion

Cited by 63

End-product inhibition of the LRRK2-counteracting PPM1H phosphatase

Adhikari, A., Tripathi, A., Chiang, C. Y., Sherpa, P., & Pfeffer, S. R. (2025) · Journal of Biological Chemistry

Protein Tyrosine PhosphatasesParkinson's Disease Mechanisms and Treatments

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