Mead, Simon

Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegeneration

Weston, P. S. J., Poole, T., Ryan, N. S., Nair, A., Liang, Y., Macpherson, K., Druyeh, R., Malone, I. B., Ahsan, R. L., Pemberton, H., et al. (2017) · Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 245

Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease

Holstege, H., Hulsman, M., Charbonnier, C., Grenier-Boley, B., Quenez, O., Grozeva, D., van Rooij, J. G. J., Sims, R., Ahmad, S., Amin, N., et al. (2022) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 226

A Novel Protective Prion Protein Variant that Colocalizes with Kuru Exposure

Mead, S., Whitfield, J., Poulter, M., Shah, P., Uphill, J., Campbell, T., Al-Dujaily, H., Hummerich, H., Beck, J., Mein, C. A., et al. (2009) · New England Journal of Medicine

Prion Diseases and Protein MisfoldingAmyloidosis: Diagnosis, Treatment, Outcomes

Cited by 206

C9orf72 expansions are the most common genetic cause of Huntington disease phenocopies

Hensman Moss, D. J., Poulter, M., Beck, J., Hehir, J., Polke, J. M., Campbell, T., Adamson, G., Mudanohwo, E., McColgan, P., Haworth, A., et al. (2014) · Neurology

Genetic Neurodegenerative DiseasesAmyotrophic Lateral Sclerosis Research

Cited by 203

Patterns of gray matter atrophy in genetic frontotemporal dementia: results from the GENFI study

Cash, D. M., Bocchetta, M., Thomas, D. L., Dick, K. M., van Swieten, J. C., Borroni, B., Galimberti, D., Masellis, M., Tartaglia, M. C., Rowe, J. B., et al. (2018) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 200

Convergent genetic and expression data implicate immunity in Alzheimer's disease

International Genomics of Alzheimer's Disease Consortium (IGAP), Jones, L., Lambert, J., Wang, L., Choi, S., Harold, D., Vedernikov, A., Escott‐Price, V., Stone, T., Richards, A., et al. (2015) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 199

Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study

van der Ende, E. L., Meeter, L. H., Poos, J. M., Panman, J. L., Jiskoot, L. C., Dopper, E. G. P., Papma, J. M., de Jong, F. J., Verberk, I. M. W., Teunissen, C., et al. (2019) · The Lancet Neurology

Amyotrophic Lateral Sclerosis ResearchDementia and Cognitive Impairment Research

Cited by 181

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

Swarup, V., Hinz, F. I., Rexach, J. E., Noguchi, K.-I., Toyoshiba, H., Oda, A., Hirai, K., Sarkar, A., Seyfried, N. T., Cheng, C., et al. (2019) · Nature Medicine

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

Cited by 136

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study

Pottier, C., Zhou, X., Perkerson, R. B., Baker, M., Jenkins, G. D., Serie, D. J., Ghidoni, R., Benussi, L., Binetti, G., López de Munain, A., et al. (2018) · The Lancet Neurology

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 131

Profiles of white matter tract pathology in frontotemporal dementia

Mahoney, C. J., Ridgway, G. R., Malone, I. B., Downey, L. E., Beck, J., Kinnunen, K. M., Schmitz, N., Golden, H. L., Rohrer, J. D., Schott, J. M., et al. (2014) · Human Brain Mapping

Dementia and Cognitive Impairment ResearchAdvanced Neuroimaging Techniques and Applications

Cited by 124

Plasma phospho-tau181 in presymptomatic and symptomatic familial Alzheimer’s disease: a longitudinal cohort study

O’Connor, A., Karikari, T. K., Poole, T., Ashton, N. J., Lantero Rodriguez, J., Khatun, A., Swift, I., Heslegrave, A. J., Abel, E., Chung, E., et al. (2021) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 122

R47H TREM2 variant increases risk of typical early‐onset Alzheimer's disease but not of prion or frontotemporal dementia

Slattery, C. F., Beck, J. A., Harper, L., Adamson, G., Abdi, Z., Uphill, J., Campbell, T., Druyeh, R., Mahoney, C. J., Rohrer, J. D., et al. (2014) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 119

Longitudinal neuroimaging and neuropsychological profiles of frontotemporal dementia with C9ORF72 expansions

Mahoney, C. J., Downey, L. E., Ridgway, G. R., Beck, J., Clegg, S., Blair, M., Finnegan, S., Leung, K. K., Yeatman, T., Golden, H., et al. (2012) · Alzheimer's Research & Therapy

Amyotrophic Lateral Sclerosis ResearchDementia and Cognitive Impairment Research

Cited by 114

A clinical study of kuru patients with long incubation periods at the end of the epidemic in Papua New Guinea

Collinge, J., Whitfield, J., McKintosh, E., Frosh, A., Mead, S., Hill, A. F., Brandner, S., Thomas, D., & Alpers, M. P. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences

Prion Diseases and Protein MisfoldingAmyloidosis: Diagnosis, Treatment, Outcomes

Cited by 110

Plasma tau is increased in frontotemporal dementia

Foiani, M. S., Woollacott, I. O., Heller, C., Bocchetta, M., Heslegrave, A., Dick, K. M., Russell, L. L., Marshall, C. R., Mead, S., Schott, J. M., et al. (2018) · Journal of Neurology, Neurosurgery & Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 64

Characterizing the Clinical Features and Atrophy Patterns of MAPT -Related Frontotemporal Dementia With Disease Progression Modeling

Young, A. L., Bocchetta, M., Russell, L. L., Convery, R. S., Peakman, G., Todd, E., Cash, D. M., Greaves, C. V., van Swieten, J., Jiskoot, L., et al. (2021) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 62

The behavioural variant frontotemporal dementia phenocopy syndrome is a distinct entity - evidence from a longitudinal study

Devenney, E., Swinn, T., Mioshi, E., Hornberger, M., Dawson, K. E., Mead, S., Rowe, J. B., & Hodges, J. R. (2018) · BMC Neurology

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 37

Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Kunkle, B., Grenier-Boley, B., Sims, R., Bis, J., Naj, A., Boland, A., Vronskaya, M., van der Lee, S., Amlie-Wolf, A., Bellenguez, C., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 35

Altered body schema processing in frontotemporal dementia with C9ORF72 mutations

Downey, L. E., Fletcher, P. D., Golden, H. L., Mahoney, C. J., Agustus, J. L., Schott, J. M., Rohrer, J. D., Beck, J., Mead, S., Rossor, M. N., et al. (2014) · Journal of Neurology, Neurosurgery & Psychiatry

Amyotrophic Lateral Sclerosis ResearchDementia and Cognitive Impairment Research

Cited by 34

Gene-Based Analysis in HRC Imputed Genome Wide Association Data Identifies Three Novel Genes For Alzheimer’s Disease

Baker, E., Sims, R., Leonenko, G., Frizzati, A., Harwood, J., Grozeva, D., GERAD/PERADES, consortia, I., Morgan, K., Passmore, P., et al. (2018) · PLoS ONE

Alzheimer's disease research and treatmentsGenetic Associations and Epidemiology

Cited by 31

Exome sequencing in a consanguineous family clinically diagnosed with early-onset Alzheimer’s disease identifies a homozygous CTSF mutation

Bras, J., Djaldetti, R., Alves, A. M., Mead, S., Darwent, L., Lleo, A., Molinuevo, J. L., Blesa, R., Singleton, A., Hardy, J., et al. (2016) · Neurobiology of Aging

Alzheimer's disease research and treatmentsLysosomal Storage Disorders Research

Cited by 27

Examining empathy deficits across familial forms of frontotemporal dementia within the GENFI cohort

Foster, P. H., Russell, L. L., Peakman, G., Convery, R. S., Bouzigues, A., Greaves, C. V., Bocchetta, M., Cash, D. M., van Swieten, J. C., Jiskoot, L. C., et al. (2022) · Cortex

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

Cited by 16

NT1-Tau Is Increased in CSF and Plasma of CJD Patients, and Correlates with Disease Progression

Mengel, D., Mok, T. H., Nihat, A., Liu, W., Rissman, R. A., Galasko, D., Zetterberg, H., Mead, S., Collinge, J., & Walsh, D. M. (2021) · Cells

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 12

Consensus meta-analysis of genome-wide association studies for Alzheimer’s disease and related dementias

EADB, Bellenguez, C., Castillo Morales, A., Amin, N., van der Lee, S. J., Muntaner, M., Parveen, K., Küçükali, F., Grenier-Boley, B., Heikkinen, S., et al. (2026) · Nature Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 7