Hein, David W.

Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis

Hein, D. W. (2002) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Pharmacogenetics and Drug MetabolismCarcinogens and Genotoxicity Assessment

Cited by 518

Inducible nitric oxide synthase is required in alcohol-induced liver injury: studies with knockout mice

McKim, S. E., Gäbele, E., Isayama, F., Lambert, J. C., Tucker, L. M., Wheeler, M. D., Connor, H. D., Mason, R. P., Doll, M. A., Hein, D. W., et al. (2003) · Gastroenterology

Alcohol Consumption and Health EffectsNitric Oxide and Endothelin Effects

Cited by 243

PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2

McDonagh, E. M., Boukouvala, S., Aklillu, E., Hein, D. W., Altman, R. B., & Klein, T. E. (2014) · Pharmacogenetics and Genomics

Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology

Cited by 146

Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms

Fretland, A. J., Leff, M. A., Doll, M. A., & Hein, D. W. (2001) · Pharmacogenetics

Pharmacogenetics and Drug MetabolismGlutathione Transferases and Polymorphisms

Cited by 141

Accuracy of Various Human NAT2 SNP Genotyping Panels to Infer Rapid, Intermediate and Slow Acetylator Phenotypes

Hein, D. W., & Doll, M. A. (2012) · Pharmacogenomics

Pharmacogenetics and Drug MetabolismGenetic Associations and Epidemiology

Cited by 121

Human arylamine N-acetyltransferase 2 genotype-dependent protein expression in cryopreserved human hepatocytes

Salazar-González, R. A., Doll, M. A., & Hein, D. W. (2020) · Scientific Reports

Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection

Cited by 21

Expression and genotype-dependent catalytic activity of N-acetyltransferase 2 (NAT2) in human peripheral blood mononuclear cells and its modulation by Sirtuin 1

Salazar-González, R. A., Turiján-Espinoza, E., Hein, D. W., Milán-Segovia, R. C., Uresti-Rivera, E. E., & Portales-Pérez, D. P. (2018) · Biochemical Pharmacology

Pharmacogenetics and Drug MetabolismGlutathione Transferases and Polymorphisms

Cited by 20

Phenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-Dependent

Millner, L. M., Doll, M. A., Cai, J., States, J. C., & Hein, D. W. (2012) · Drug Metabolism and Disposition

Pharmacogenetics and Drug MetabolismGlutathione Transferases and Polymorphisms

Cited by 17

Arylamine N-acetyltransferase 1 activity is regulated by the protein acetylation status

Salazar-González, R. A., Doll, M. A., & Hein, D. W. (2022) · Frontiers in Pharmacology

Histone Deacetylase Inhibitors ResearchPharmacogenetics and Drug Metabolism

Cited by 9