Easton, Amy

Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science

Circadian rhythm and melatoninRegulation of Appetite and Obesity

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Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology

Lee, S.-H., Meilandt, W. J., Xie, L., Gandham, V. D., Ngu, H., Barck, K. H., Rezzonico, M. G., Imperio, J., Lalehzadeh, G., Huntley, M. A., et al. (2021) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model

Meilandt, W. J., Ngu, H., Gogineni, A., Lalehzadeh, G., Lee, S.-H., Srinivasan, K., Imperio, J., Wu, T., Weber, M., Kruse, A. J., et al. (2020) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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The circadian Clock mutation increases exploratory activity and escape-seeking behavior

Easton, A., Arbuzova, J., & Turek, F. W. (2003) · Genes, Brain and Behavior

Circadian rhythm and melatoninNeurotransmitter Receptor Influence on Behavior

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Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimer’s Disease and Multiple Sclerosis

Etxeberria, A., Shen, Y.-A. A., Vito, S., Silverman, S. M., Imperio, J., Lalehzadeh, G., Soung, A. L., Du, C., Xie, L., Choy, M. K., et al. (2024) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

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The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia

Bristow, L. J., Easton, A. E., Li, Y.-W., Sivarao, D. V., Lidge, R., Jones, K. M., Post-Munson, D., Daly, C., Lodge, N. J., Gallagher, L., et al. (2016) · PLOS ONE

Nicotinic Acetylcholine Receptors StudySchizophrenia research and treatment

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