Morris, John P.

Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma

Kopp, J. L., von Figura, G., Mayes, E., Liu, F.-F., Dubois, C. L., Morris, J. P., Pan, F. C., Akiyama, H., Wright, C. V. E., Jensen, K., et al. (2012) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchCancer Cells and Metastasis

Cited by 697

Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling

Weissmueller, S., Manchado, E., Saborowski, M., Morris, J. P., Wagenblast, E., Davis, C. A., Moon, S.-H., Pfister, N. T., Tschaharganeh, D. F., Kitzing, T., et al. (2014) · Cell

Cancer-related Molecular PathwaysPancreatic and Hepatic Oncology Research

Cited by 466

Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer

Ruscetti, M., Morris, J. P., Mezzadra, R., Russell, J., Leibold, J., Romesser, P. B., Simon, J., Kulick, A., Ho, Y.-J., Fennell, M., et al. (2020) · Cell

Pancreatic and Hepatic Oncology ResearchTelomeres, Telomerase, and Senescence

Cited by 424

A combinatorial strategy for treating KRAS-mutant lung cancer

Manchado, E., Weissmueller, S., Morris, J. P., Chen, C.-C., Wullenkord, R., Lujambio, A., de Stanchina, E., Poirier, J. T., Gainor, J. F., Corcoran, R. B., et al. (2016) · Nature

Lung Cancer Treatments and MutationsProtein Kinase Regulation and GTPase Signaling

Cited by 403

α-Ketoglutarate links p53 to cell fate during tumour suppression

Morris, J. P., Yashinskie, J. J., Koche, R., Chandwani, R., Tian, S., Chen, C.-C., Baslan, T., Marinkovic, Z. S., Sánchez-Rivera, F. J., Leach, S. D., et al. (2019) · Nature

Cancer-related Molecular PathwaysCancer, Hypoxia, and Metabolism

Cited by 296

Ordered and deterministic cancer genome evolution after p53 loss

Baslan, T., Morris, J. P., Zhao, Z., Reyes, J., Ho, Y.-J., Tsanov, K. M., Bermeo, J., Tian, S., Zhang, S., Askan, G., et al. (2022) · Nature

Cancer Genomics and DiagnosticsCancer-related Molecular Pathways

Cited by 221

Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation

von Figura, G., Morris, J. P., Wright, C. V. E., & Hebrok, M. (2014) · Gut

Pancreatic and Hepatic Oncology ResearchPancreatic function and diabetes

Cited by 143

Arid1a restrains Kras-dependent changes in acinar cell identity

Livshits, G., Alonso-Curbelo, D., Morris, J. P., Koche, R., Saborowski, M., Wilkinson, J. E., & Lowe, S. W. (2018) · eLife

Chromatin Remodeling and CancerPancreatic and Hepatic Oncology Research

Cited by 48

Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer

Ruscetti, M., Morris, J. P., Mezzadra, R., Russell, J., Leibold, J., Romesser, P. B., Simon, J., Kulick, A., Ho, Y.-J., Fennell, M., et al. (2021) · Cell

Pancreatic and Hepatic Oncology ResearchTelomeres, Telomerase, and Senescence

Cited by 46