Schittenhelm, Ralf B.

Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance

Xirouchaki, C. E., Jia, Y., McGrath, M. J., Greatorex, S., Tran, M., Merry, T. L., Hong, D., Eramo, M. J., Broome, S. C., Woodhead, J. S. T., et al. (2021) · Science Advances

Redox biology and oxidative stressExercise and Physiological Responses

Cited by 107

SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control

Montgomery, M. K., Bayliss, J., Devereux, C., Bezawork-Geleta, A., Roberts, D., Huang, C., Schittenhelm, R. B., Ryan, A., Townley, S. L., Selth, L. A., et al. (2020) · Science Translational Medicine

Adipokines, Inflammation, and Metabolic DiseasesDiabetes Treatment and Management

Cited by 63

A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling

Koch, B., Barugahare, A. A., Lo, T. L., Huang, C., Schittenhelm, R. B., Powell, D. R., Beilharz, T. H., & Traven, A. (2018) · Cell Reports

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 50

Molecular Landscape of Sex- and Modality-Specific Exercise Adaptation in Human Skeletal Muscle through Large-Scale Multi-Omics Integration

Jacques, M., Landen, S., Sharples, A. P., Garnham, A., Schittenhelm, R., Steele, J., Heikkinen, A., Sillanpää, E., Ollikainen, M., Broatch, J., et al. (2025) · Cell Reports

Genetics and Physical PerformanceCardiovascular and exercise physiology

Cited by 23

Mycobacteria Tolerate Carbon Monoxide by Remodeling Their Respiratory Chain

Bayly, K., Cordero, P. R. F., Kropp, A., Huang, C., Schittenhelm, R. B., Grinter, R., & Greening, C. (2021) · mSystems

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 20

Structure of a Rhs effector clade domain provides mechanistic insights into type VI secretion system toxin delivery

Hayes, B. K., Harper, M., Venugopal, H., Lewis, J. M., Wright, A., Lee, H.-C., Steele, J. R., Steer, D. L., Schittenhelm, R. B., Boyce, J. D., et al. (2024) · Nature Communications

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 15

Structure of a Rhs effector clade domain identifies new mechanistic insights into type VI secretion system toxin delivery.

McGowan, S., Hayes, B., Harper, M., Venugopal, H., Lewis, J., Wright, A., Steele, J., Steer, D., Schittenhelm, R., & Boyce, J. (2023) · Nature Communications

Bacterial Genetics and BiotechnologyEscherichia coli research studies

Cited by 15

Ubr1-induced selective endophagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress

Wang, B. B., Xu, H., Isenmann, S., Huang, C., Elorza-Vidal, X., Rychkov, G. Y., Estévez, R., Schittenhelm, R. B., Lukacs, G. L., & Apaja, P. M. (2022) · Cellular and Molecular Life Sciences

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 10

Ubr1-induced selective endo-phagy/autophagy protects against the endosomal and Ca 2+ -induced proteostasis disease stress

Wang, B. B., Xu, H., Isenmann, S., Huang, C., Elorza-Vidal, X., Rychkov, G. Y., Estévez, R., Schittenhelm, R. B., Lukacs, G. L., & Apaja, P. M. (2021) · Cellular and Molecular Life Sciences

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 10