Swaney, Danielle L.

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Gordon, D. E., Jang, G. M., Bouhaddou, M., Xu, J., Obernier, K., White, K. M., O’Meara, M. J., Rezelj, V. V., Guo, J. Z., Swaney, D. L., et al. (2020) · Nature

SARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery Methods

Cited by 4,405

The functional landscape of the human phosphoproteome

Ochoa, D., Jarnuczak, A. F., Viéitez, C., Gehre, M., Soucheray, M., Mateus, A., Kleefeldt, A. A., Hill, A., Garcia-Alonso, L., Stein, F., et al. (2020) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 491

Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome

Bourdenx, M., Martín-Segura, A., Scrivo, A., Rodriguez-Navarro, J. A., Kaushik, S., Tasset, I., Diaz, A., Storm, N. J., Xin, Q., Juste, Y. R., et al. (2021) · Cell

Autophagy in Disease and TherapyHeat shock proteins research

Cited by 337

KRAS G12C inhibition produces a driver-limited state revealing collateral dependencies

Lou, K., Steri, V., Ge, A. Y., Hwang, Y. C., Yogodzinski, C. H., Shkedi, A. R., Choi, A. L. M., Mitchell, D. C., Swaney, D. L., Hann, B., et al. (2019) · Science Signaling

Protein Kinase Regulation and GTPase SignalingCancer Genomics and Diagnostics

Cited by 175

Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function

Orr, A. L., Kim, C., Jimenez-Morales, D., Newton, B. W., Johnson, J. R., Krogan, N. J., Swaney, D. L., & Mahley, R. W. (2019) · Journal of Alzheimer's Disease

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 103

Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

Thorne, L. G., Bouhaddou, M., Reuschl, A.-K., Zuliani-Alvarez, L., Polacco, B., Pelin, A., Batra, J., Whelan, M. V. X., Ummadi, M., Rojc, A., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

SARS-CoV-2 and COVID-19 Researchinterferon and immune responses

Cited by 91

CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes

Gupta, M., Azumaya, C. M., Moritz, M., Pourmal, S., Diallo, A., Merz, G. E., Jang, G., Bouhaddou, M., Fossati, A., Brilot, A. F., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

SARS-CoV-2 and COVID-19 ResearchAdvanced Electron Microscopy Techniques and Applications

Cited by 89

Interpretation of cancer mutations using a multiscale map of protein systems

Zheng, F., Kelly, M. R., Ramms, D. J., Heintschel, M. L., Tao, K., Tutuncuoglu, B., Lee, J. J., Ono, K., Foussard, H., Chen, M., et al. (2021) · Science

Bioinformatics and Genomic NetworksCancer Genomics and Diagnostics

Cited by 81

Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis

Paulo, E., Wu, D., Wang, Y., Zhang, Y., Wu, Y., Swaney, D. L., Soucheray, M., Jimenez-Morales, D., Chawla, A., Krogan, N. J., et al. (2018) · Scientific Reports

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 59

Reduced endosomal microautophagy activity in aging associates with enhanced exocyst‐mediated protein secretion

Krause, G. J., Diaz, A., Jafari, M., Khawaja, R. R., Agullo‐Pascual, E., Santiago‐Fernández, O., Richards, A. L., Chen, K., Dmitriev, P., Sun, Y., et al. (2022) · Aging Cell

Autophagy in Disease and TherapyCellular transport and secretion

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Functional analysis of a common BAG3 allele associated with protection from heart failure

Perez-Bermejo, J. A., Judge, L. M., Jensen, C. L., Wu, K., Watry, H. L., Truong, A., Ho, J. J., Carter, M., Runyon, W. V., Kaake, R. M., et al. (2023) · Nature Cardiovascular Research

Heat shock proteins researchCardiac electrophysiology and arrhythmias

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