Grandis, Jennifer R.

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

Johnson, D. E., O'Keefe, R. A., & Grandis, J. R. (2018) · Nature Reviews Clinical Oncology

Cytokine Signaling Pathways and InteractionsTGF-β signaling in diseases

Cited by 3,110

STAT signaling in head and neck cancer

Song, J. I., & Grandis, J. R. (2000) · Oncogene

Cytokine Signaling Pathways and InteractionsHead and Neck Cancer Studies

Cited by 374

First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy

Sen, M., Thomas, S. M., Kim, S., Yeh, J. I., Ferris, R. L., Johnson, J. T., Duvvuri, U., Lee, J., Sahu, N., Joyce, S., et al. (2012) · Cancer Discovery

Cytokine Signaling Pathways and InteractionsRNA Interference and Gene Delivery

Cited by 313

The STAT3 pathway as a therapeutic target in head and neck cancer: barriers and innovations

Geiger, J. L., Grandis, J. R., & Bauman, J. E. (2016) · Oral Oncology

Cytokine Signaling Pathways and InteractionsHead and Neck Cancer Studies

Cited by 193

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response.

Liao, H.-W., Hsu, J.-M., Xia, W., Wang, H.-L., Wang, Y.-N., Chang, W.-C., Arold, S. T., Chou, C.-K., Tsou, P.-H., Yamaguchi, H., et al. (2015) · Journal of Clinical Investigation

HER2/EGFR in Cancer ResearchCancer-related gene regulation

Cited by 155

Lack of toxicity of a STAT3 decoy oligonucleotide

Sen, M., Tosca, P. J., Zwayer, C., Ryan, M. J., Johnson, J. D., Knostman, K. A. B., Giclas, P. C., Peggins, J. O., Tomaszewski, J. E., McMurray, T. P., et al. (2009) · Cancer Chemotherapy and Pharmacology

Cytokine Signaling Pathways and InteractionsRNA Interference and Gene Delivery

Cited by 53

Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer

Panupinthu, N., Yu, S., Zhang, D., Zhang, F., Gagea, M., Lu, Y., Grandis, J. R., Dunn, S. E., Lee, H. Y., & Mills, G. B. (2014) · Oncogene

Ovarian cancer diagnosis and treatmentHER2/EGFR in Cancer Research

Cited by 49