Lennernäs, Hans

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Amidon, G. L., Lennernäs, H., Shah, V. P., & Crison, J. R. (1995) · Pharmaceutical Research

Drug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems

Cited by 5,430

Pharmacodynamics and Pharmacokinetics of the HMG-CoA Reductase Inhibitors: Similarities and Differences

Lennernäs, H., & Fager, G. (1997) · Clinical Pharmacokinetics

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 527

Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation

Johannsson, G., Nilsson, A. G., Bergthorsdottir, R., Burman, P., Dahlqvist, P., Ekman, B., Engström, B. E., Olsson, T., Ragnarsson, O., Ryberg, M., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersHormonal and reproductive studies

Cited by 329

Intestinal permeability and its relevance for absorption and elimination

Lennernäs, H. (2007) · Xenobiotica

Drug Solubulity and Delivery SystemsDrug Transport and Resistance Mechanisms

Cited by 304

In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: application of the mechanistic absorption model GI-Sim

Sjögren, E., Westergren, J., Grant, I., Hanisch, G., Lindfors, L., Lennernäs, H., Abrahamsson, B., & Tannergren, C. (2013) · European Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsPharmaceutical studies and practices

Cited by 168

Adrenal insufficiency: review of clinical outcomes with current glucocorticoid replacement therapy

Johannsson, G., Falorni, A., Skrtic, S., Lennernäs, H., Quinkler, M., Monson, J. P., & Stewart, P. M. (2015) · Clinical Endocrinology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 122

Regional intestinal drug permeation: Biopharmaceutics and drug development

Lennernäs, H. (2014) · European Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsAdvanced Drug Delivery Systems

Cited by 103

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Margolskee, A., Darwich, A. S., Pepin, X., Aarons, L., Galetin, A., Rostami-Hodjegan, A., Carlert, S., Hammarberg, M., Hilgendorf, C., Johansson, P., et al. (2017) · European Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsPharmaceutical studies and practices

Cited by 69

Miniaturized nebulization catheters: a new approach for delivery of defined aerosol doses to the rat lung

Tronde, A., Baran, G., Eirefelt, S., Lennernäs, H., & Bengtsson, U. H. (2002) · Journal of Aerosol Medicine

Inhalation and Respiratory Drug DeliveryAdvanced Drug Delivery Systems

Cited by 45

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Darwich, A. S., Margolskee, A., Pepin, X., Aarons, L., Galetin, A., Rostami-Hodjegan, A., Carlert, S., Hammarberg, M., Hilgendorf, C., Johansson, P., et al. (2017) · European Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsComputational Drug Discovery Methods

Cited by 45

Bioequivalence of Oral Products and the Biopharmaceutics Classification System: Science, Regulation, and Public Policy

Amidon, K. S., Langguth, P., Lennernäs, H., Yu, L., & Amidon, G. L. (2011) · Clinical Pharmacology & Therapeutics

Drug Solubulity and Delivery SystemsPharmaceutical Economics and Policy

Cited by 44

IMI – oral biopharmaceutics tools project – evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

Margolskee, A., Darwich, A. S., Pepin, X., Pathak, S. M., Bolger, M. B., Aarons, L., Rostami-Hodjegan, A., Angstenberger, J., Graf, F., Laplanche, L., et al. (2017) · European Journal of Pharmaceutical Sciences

Drug Solubulity and Delivery SystemsPharmaceutical studies and practices

Cited by 43

Effect on the Gastrointestinal Absorption of Drugs from Different Classes in the Biopharmaceutics Classification System, When Treating with Liraglutide

Malm-Erjefält, M., Ekblom, M., Vouis, J., Zdravkovic, M., & Lennernäs, H. (2015) · Molecular Pharmaceutics

Drug Solubulity and Delivery SystemsPharmacogenetics and Drug Metabolism

Cited by 36

Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction

Prieto Garcia, L., Lundahl, A., Ahlström, C., Vildhede, A., Lennernäs, H., & Sjögren, E. (2022) · CPT: Pharmacometrics & Systems Pharmacology

Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices

Cited by 21

Improving outcomes in patients with adrenal insufficiency: a review of current and future treatments

Johannsson, G., Skrtic, S., Lennernäs, H., Quinkler, M., & Stewart, P. M. (2014) · Current Medical Research and Opinion

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 21