Ramracheya, Reshma

Voltage-Gated Ion Channels in Human Pancreatic β-Cells: Electrophysiological Characterization and Role in Insulin Secretion

Braun, M., Ramracheya, R., Bengtsson, M., Zhang, Q., Karanauskaite, J., Partridge, C., Johnson, P. R., & Rorsman, P. (2008) · Diabetes

Pancreatic function and diabetesIon channel regulation and function

Cited by 417

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose

Brereton, M. F., Iberl, M., Shimomura, K., Zhang, Q., Adriaenssens, A. E., Proks, P., Spiliotis, I. I., Dace, W., Mattis, K. K., Ramracheya, R., et al. (2014) · Nature Communications

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 259

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

De Marinis, Y. Z., Salehi, A., Ward, C. E., Zhang, Q., Abdulkader, F., Bengtsson, M., Braha, O., Braun, M., Ramracheya, R., Amisten, S., et al. (2010) · Cell Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 257

γ-Aminobutyric Acid (GABA) Is an Autocrine Excitatory Transmitter in Human Pancreatic β-Cells

Braun, M., Ramracheya, R., Bengtsson, M., Clark, A., Walker, J. N., Johnson, P. R., & Rorsman, P. (2010) · Diabetes

Pancreatic function and diabetesNeuroscience and Neuropharmacology Research

Cited by 239

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes

Rosengren, A. H., Braun, M., Mahdi, T., Andersson, S. A., Travers, M. E., Shigeto, M., Zhang, E., Almgren, P., Ladenvall, C., Axelsson, A. S., et al. (2012) · Diabetes

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 237

Role of KATP Channels in Glucose-Regulated Glucagon Secretion and Impaired Counterregulation in Type 2 Diabetes

Zhang, Q., Ramracheya, R., Lahmann, C., Tarasov, A., Bengtsson, M., Braha, O., Braun, M., Brereton, M., Collins, S., Galvanovskis, J., et al. (2013) · Cell Metabolism

Pancreatic function and diabetesIon channel regulation and function

Cited by 225

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

Shigeto, M., Ramracheya, R., Tarasov, A. I., Cha, C. Y., Chibalina, M. V., Hastoy, B., Philippaert, K., Reinbothe, T., Rorsman, N., Salehi, A., et al. (2015) · Journal of Clinical Investigation

Pancreatic function and diabetesIon Channels and Receptors

Cited by 189

Function and expression of melatonin receptors on human pancreatic islets

Ramracheya, R. D., Muller, D. S., Squires, P. E., Brereton, H., Sugden, D., Huang, G. C., Amiel, S. A., Jones, P. M., & Persaud, S. J. (2008) · Journal of Pineal Research

Pancreatic function and diabetesCircadian rhythm and melatonin

Cited by 186

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion

Vergari, E., Knudsen, J. G., Ramracheya, R., Salehi, A., Zhang, Q., Adam, J., Asterholm, I. W., Benrick, A., Briant, L. J. B., Chibalina, M. V., et al. (2019) · Nature Communications

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 152

Chronic Palmitate Exposure Inhibits Insulin Secretion by Dissociation of Ca2+ Channels from Secretory Granules

Hoppa, M. B., Collins, S., Ramracheya, R., Hodson, L., Amisten, S., Zhang, Q., Johnson, P., Ashcroft, F. M., & Rorsman, P. (2009) · Cell Metabolism

Pancreatic function and diabetesCellular transport and secretion

Cited by 152

Membrane Potential-Dependent Inactivation of Voltage-Gated Ion Channels in α-Cells Inhibits Glucagon Secretion From Human Islets

Ramracheya, R., Ward, C., Shigeto, M., Walker, J. N., Amisten, S., Zhang, Q., Johnson, P. R., Rorsman, P., & Braun, M. (2010) · Diabetes

Pancreatic function and diabetesIon channel regulation and function

Cited by 136

GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca 2+ channels

Ramracheya, R., Chapman, C., Chibalina, M., Dou, H., Miranda, C., González, A., Moritoh, Y., Shigeto, M., Zhang, Q., Braun, M., et al. (2018) · Physiological Reports

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 128

Na+ current properties in islet α‐ and β‐cells reflect cell‐specific Scn3a and Scn9a expression

Zhang, Q., Chibalina, M. V., Bengtsson, M., Groschner, L. N., Ramracheya, R., Rorsman, N. J. G., Leiss, V., Nassar, M. A., Welling, A., Gribble, F. M., et al. (2014) · The Journal of Physiology

Ion channel regulation and functionPancreatic function and diabetes

Cited by 90

Progression of Diet-Induced Diabetes in C57BL6J Mice Involves Functional Dissociation of Ca2+ Channels From Secretory Vesicles

Collins, S. C., Hoppa, M. B., Walker, J. N., Amisten, S., Abdulkader, F., Bengtsson, M., Fearnside, J., Ramracheya, R., Toye, A. A., Zhang, Q., et al. (2010) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 73

Exocytotic Properties of Human Pancreatic β‐cells

Braun, M., Ramracheya, R., Johnson, P. R., & Rorsman, P. (2009) · Annals of the New York Academy of Sciences

Pancreatic function and diabetesCellular transport and secretion

Cited by 60

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta cells

Vergari, E., Denwood, G., Salehi, A., Zhang, Q., Adam, J., Alrifaiy, A., Wernstedt Asterholm, I., Benrick, A., Chibalina, M. V., Eliasson, L., et al. (2020) · Nature Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 43

GLP-1 metabolite GLP-1(9–36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion

Gandasi, N. R., Gao, R., Kothegala, L., Pearce, A., Santos, C., Acreman, S., Basco, D., Benrick, A., Chibalina, M. V., Clark, A., et al. (2024) · Diabetologia

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 31