Marnett, Lawrence J.

Identification and Functional Characterization of Brainstem Cannabinoid CB2Receptors

Van Sickle, M. D., Duncan, M., Kingsley, P. J., Mouihate, A., Urbani, P., Mackie, K., Stella, N., Makriyannis, A., Piomelli, D., Davison, J. S., et al. (2005) · Science

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

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Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2

Kozak, K. R., Rowlinson, S. W., & Marnett, L. J. (2000) · Journal of Biological Chemistry

Cannabis and Cannabinoid ResearchInflammatory mediators and NSAID effects

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Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides

Kozak, K. R., Crews, B. C., Morrow, J. D., Wang, L.-H., Ma, Y. H., Weinander, R., Jakobsson, P.-J., & Marnett, L. J. (2002) · Journal of Biological Chemistry

Cannabis and Cannabinoid ResearchInflammatory mediators and NSAID effects

Cited by 368

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H 2 synthases

Boutaud, O., Aronoff, D. M., Richardson, J. H., Marnett, L. J., & Oates, J. A. (2002) · Proceedings of the National Academy of Sciences

Inflammatory mediators and NSAID effectsEicosanoids and Hypertension Pharmacology

Cited by 209

Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation

Bluett, R. J., Gamble-George, J. C., Hermanson, D. J., Hartley, N. D., Marnett, L. J., & Patel, S. (2014) · Translational Psychiatry

Cannabis and Cannabinoid ResearchStress Responses and Cortisol

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Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation

Shonesy, B. C., Bluett, R. J., Ramikie, T. S., Báldi, R., Hermanson, D. J., Kingsley, P. J., Marnett, L. J., Winder, D. G., Colbran, R. J., & Patel, S. (2014) · Cell Reports

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 155

Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala

Patel, S., Kingsley, P. J., Mackie, K., Marnett, L. J., & Winder, D. G. (2009) · Neuropsychopharmacology

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

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Cyclooxygenase mechanisms

Marnett, L. J. (2000) · Current Opinion in Chemical Biology

Metal-Catalyzed Oxygenation MechanismsInflammatory mediators and NSAID effects

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Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation

Hermanson, D. J., Hartley, N. D., Gamble-George, J., Brown, N., Shonesy, B. C., Kingsley, P. J., Colbran, R. J., Reese, J., Marnett, L. J., & Patel, S. (2013) · Nature Neuroscience

Cannabis and Cannabinoid ResearchInflammatory mediators and NSAID effects

Cited by 126

Nitroarachidonic acid, a novel peroxidase inhibitor of prostaglandin endoperoxide H synthases 1 and 2

Trostchansky, A., Bonilla, L., Thomas, C. P., O'Donnell, V. B., Marnett, L. J., Radi, R., & Rubbo, H. (2011) · Journal of Biological Chemistry

Inflammatory mediators and NSAID effectsEicosanoids and Hypertension Pharmacology

Cited by 58

Cyclooxygenase-2 inhibition reduces stress-induced affective pathology

Gamble-George, J. C., Baldi, R., Halladay, L., Kocharian, A., Hartley, N., Silva, C. G., Roberts, H., Haymer, A., Marnett, L. J., Holmes, A., et al. (2016) · eLife

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

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