Burt, Alastair

Cellular senescence drives age-dependent hepatic steatosis

Ogrodnik, M., Miwa, S., Tchkonia, T., Tiniakos, D., Wilson, C. L., Lahat, A., Day, C. P., Burt, A., Palmer, A., Anstee, Q. M., et al. (2017) · Nature Communications

Telomeres, Telomerase, and SenescenceLiver Disease Diagnosis and Treatment

Cited by 1,044

Age as a confounding factor for the accurate non-invasive diagnosis of advanced NAFLD fibrosis

McPherson, S., Hardy, T., Dufour, J.-F., Petta, S., Romero-Gomez, M., Allison, M., Oliveira, C. P., Francque, S., Van Gaal, L., Schattenberg, J. M., et al. (2017) · American Journal of Gastroenterology

Liver Disease Diagnosis and TreatmentLiver Disease and Transplantation

Cited by 945

TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease

Liu, Y.-L., Reeves, H. L., Burt, A. D., Tiniakos, D., McPherson, S., Leathart, J. B. S., Allison, M. E. D., Alexander, G. J., Piguet, A.-C., Anty, R., et al. (2014) · Nature Communications

Liver Disease Diagnosis and TreatmentGenetic Associations and Epidemiology

Cited by 623

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

Shalapour, S., Lin, X.-J., Bastian, I. N., Brain, J., Burt, A. D., Aksenov, A. A., Vrbanac, A. F., Li, W., Perkins, A., Matsutani, T., et al. (2017) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 589

Carriage of the PNPLA3 rs738409 C >G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma

Liu, Y.-L., Patman, G. L., Leathart, J. B. S., Piguet, A.-C., Burt, A. D., Dufour, J.-F., Day, C. P., Daly, A. K., Reeves, H. L., & Anstee, Q. M. (2014) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentHepatocellular Carcinoma Treatment and Prognosis

Cited by 549

Genome-wide association study of non-alcoholic fatty liver and steatohepatitis in a histologically characterised cohort☆

Anstee, Q. M., Darlay, R., Cockell, S., Meroni, M., Govaere, O., Tiniakos, D., Burt, A. D., Bedossa, P., Palmer, J., Liu, Y.-L., et al. (2020) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentGenetic Associations and Epidemiology

Cited by 499

Multigenerational epigenetic adaptation of the hepatic wound-healing response

Zeybel, M., Hardy, T., Wong, Y. K., Mathers, J. C., Fox, C. R., Gackowska, A., Oakley, F., Burt, A. D., Wilson, C. L., Anstee, Q. M., et al. (2012) · Nature Medicine

Liver physiology and pathologyEpigenetics and DNA Methylation

Cited by 279

Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease

Ebrahimkhani, M. R., Oakley, F., Murphy, L. B., Mann, J., Moles, A., Perugorria, M. J., Ellis, E., Lakey, A. F., Burt, A. D., Douglass, A., et al. (2011) · Nature Medicine

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 221

Immune response towards lipid peroxidation products as a predictor of progression of non‐alcoholic fatty liver disease to advanced fibrosis

Albano, E., Mottaran, E., Vidali, M., Reale, E., Saksena, S., Occhino, G., Burt, A. D., & Day, C. P. (2005) · Gut

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 219

Performance of non-invasive tests and histology for the prediction of clinical outcomes in patients with non-alcoholic fatty liver disease: an individual participant data meta-analysis

Mózes, F. E., Lee, J. A., Vali, Y., Alzoubi, O., Staufer, K., Trauner, M., Paternostro, R., Stauber, R. E., Holleboom, A. G., van Dijk, A.-M., et al. (2023) · The Lancet Gastroenterology & Hepatology

Liver Disease Diagnosis and TreatmentLiver Disease and Transplantation

Cited by 214

Primary biliary cirrhosis once rare, now common in the United Kingdom?

James, O. F., Bhopal, R., Howel, D., Gray, J., Burt, A. D., & Metcalf, J. V. (1999) · Hepatology

Liver Diseases and ImmunityPediatric Hepatobiliary Diseases and Treatments

Cited by 213

Exercise Reduces Liver Lipids and Visceral Adiposity in Patients With Nonalcoholic Steatohepatitis in a Randomized Controlled Trial

Houghton, D., Thoma, C., Hallsworth, K., Cassidy, S., Hardy, T., Burt, A. D., Tiniakos, D., Hollingsworth, K. G., Taylor, R., Day, C. P., et al. (2017) · Clinical Gastroenterology and Hepatology

Liver Disease Diagnosis and TreatmentPhysical Activity and Health

Cited by 209

Caucasian lean subjects with non-alcoholic fatty liver disease share long-term prognosis of non-lean: time for reappraisal of BMI-driven approach?

Younes, R., Govaere, O., Petta, S., Miele, L., Tiniakos, D., Burt, A., David, E., Vecchio, F. M., Maggioni, M., Cabibi, D., et al. (2022) · Gut

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 205

Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosis

Prince, M. I., Burt, A. D., & Jones, D. E. J. (2002) · Gut

Drug-Induced Hepatotoxicity and ProtectionLiver Diseases and Immunity

Cited by 202

Long-term outcomes and predictive ability of non-invasive scoring systems in patients with non-alcoholic fatty liver disease

Younes, R., Caviglia, G. P., Govaere, O., Rosso, C., Armandi, A., Sanavia, T., Pennisi, G., Liguori, A., Francione, P., Gallego-Durán, R., et al. (2021) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver Disease and Transplantation

Cited by 196

Serum Immunoglobulin Levels Predict Fibrosis in Patients With Non-Alcoholic Fatty Liver Disease

McPherson, S., Henderson, E., Burt, A. D., Day, C. P., & Anstee, Q. M. (2014) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver Diseases and Immunity

Cited by 124

Deep learning uncertainty and confidence calibration for the five-class polyp classification from colonoscopy

Carneiro, G., Zorron Cheng Tao Pu, L., Singh, R., & Burt, A. (2020) · Medical Image Analysis

Colorectal Cancer Screening and DetectionExplainable Artificial Intelligence (XAI)

Cited by 76

AI-based automation of enrollment criteria and endpoint assessment in clinical trials in liver diseases

Iyer, J. S., Juyal, D., Le, Q., Shanis, Z., Pokkalla, H., Pouryahya, M., Pedawi, A., Stanford-Moore, S. A., Biddle-Snead, C., Carrasco-Zevallos, O., et al. (2024) · Nature Medicine

Liver Disease Diagnosis and TreatmentArtificial Intelligence in Healthcare and Education

Cited by 54

Drug-Induced Hepatocellular Injury Due to Herbal Supplement Ashwagandha

Ireland, P. J., Hardy, T., Burt, A. D., & Donnelly, M. C. (2021) · Journal of the Royal College of Physicians of Edinburgh

Drug-Induced Hepatotoxicity and ProtectionComplementary and Alternative Medicine Studies

Cited by 27

TOP-289 Artificial intelligence-based measurement of non-alcoholic steatohepatitis is an accurate tool for clinical trial enrollment and end point assessment

Pulaski, H., Hou, H., Resnick, M., Harrison, S. A., Sanyal, A. J., Ratziu, V., Burt, A., Bedossa, P., Montalto, M., & Wack, K. (2024) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentArtificial Intelligence in Healthcare and Education

Cited by 1