Wood, Matthew J. A.

Genome-wide atlas of gene expression in the adult mouse brain

Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., et al. (2007) · Nature

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 5,572

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Alvarez-Erviti, L., Seow, Y., Yin, H., Betts, C., Lakhal, S., & Wood, M. J. A. (2011) · Nature Biotechnology

RNA Interference and Gene DeliveryExtracellular vesicles in disease

Cited by 4,930

Extracellular vesicles: biology and emerging therapeutic opportunities

EL Andaloussi, S., Mäger, I., Breakefield, X. O., & Wood, M. J. A. (2013) · Nature Reviews Drug Discovery

Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery

Cited by 3,571

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

Wiklander, O. P. B., Nordin, J. Z., O'Loughlin, A., Gustafsson, Y., Corso, G., Mäger, I., Vader, P., Lee, Y., Sork, H., Seow, Y., et al. (2015) · Journal of Extracellular Vesicles

Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery

Cited by 1,730

Antisense oligonucleotides: the next frontier for treatment of neurological disorders

Rinaldi, C., & Wood, M. J. A. (2018) · Nature Reviews Neurology

RNA Interference and Gene DeliveryNeurogenetic and Muscular Disorders Research

Cited by 788

Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles

Kooijmans, S. A. A., Stremersch, S., Braeckmans, K., de Smedt, S. C., Hendrix, A., Wood, M. J. A., Schiffelers, R. M., Raemdonck, K., & Vader, P. (2013) · Journal of Controlled Release

RNA Interference and Gene DeliveryExtracellular vesicles in disease

Cited by 663

Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER

Heusermann, W., Hean, J., Trojer, D., Steib, E., von Bueren, S., Graff-Meyer, A., Genoud, C., Martin, K., Pizzato, N., Voshol, J., et al. (2016) · Journal of Cell Biology

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 447

Extracellular vesicles in neurodegenerative disease — pathogenesis to biomarkers

Thompson, A. G., Gray, E., Heman-Ackah, S. M., Mäger, I., Talbot, K., Andaloussi, S. E., Wood, M. J., & Turner, M. R. (2016) · Nature Reviews Neurology

Extracellular vesicles in diseaseNanoparticle-Based Drug Delivery

Cited by 431

Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

Papadakis, M., Hadley, G., Xilouri, M., Hoyte, L. C., Nagel, S., McMenamin, M. M., Tsaknakis, G., Watt, S. M., Drakesmith, C. W., Chen, R., et al. (2013) · Nature Medicine

Autophagy in Disease and TherapyNeurological Disease Mechanisms and Treatments

Cited by 232

The viral protein corona directs viral pathogenesis and amyloid aggregation

Ezzat, K., Pernemalm, M., Pålsson, S., Roberts, T. C., Järver, P., Dondalska, A., Bestas, B., Sobkowiak, M. J., Levänen, B., Sköld, M., et al. (2019) · Nature Communications

Alzheimer's disease research and treatmentsNanoparticle-Based Drug Delivery

Cited by 209

The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation

Couch, Y., Alvarez-Erviti, L., Sibson, N. R., Wood, M. J., & Anthony, D. C. (2011) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 155

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome

Sork, H., Corso, G., Krjutskov, K., Johansson, H. J., Nordin, J. Z., Wiklander, O. P. B., Lee, Y. X. F., Westholm, J. O., Lehtiö, J., Wood, M. J. A., et al. (2018) · Scientific Reports

Extracellular vesicles in diseaseRNA Interference and Gene Delivery

Cited by 140

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

Dar, G. H., Mendes, C. C., Kuan, W.-L., Speciale, A. A., Conceição, M., Görgens, A., Uliyakina, I., Lobo, M. J., Lim, W. F., EL Andaloussi, S., et al. (2021) · Nature Communications

Extracellular vesicles in diseaseRNA Interference and Gene Delivery

Cited by 100

High Soluble Amyloid‐β42 Predicts Normal Cognition in Amyloid‐Positive Individuals With Alzheimer's Disease‐Causing Mutations

Sturchio, A., (DIAN), T. D. I. A. C., Dwivedi, A. K., Malm, T., Wood, M. J. A., Cilia, R., Sharma, J. S., Hill, E. J., Schneider, L. S., Graff-Radford, N. R., et al. (2022) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57

Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity

Vázquez-Vélez, G. E., Gonzales, K. A., Revelli, J.-P., Adamski, C. J., Alavi Naini, F., Bajić, A., Craigen, E., Richman, R., Heman-Ackah, S. M., Wood, M. J. A., et al. (2020) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 22

Wrangling RNA: Antisense oligonucleotides for neurological disorders

Talbot, K., & Wood, M. J. A. (2019) · Science Translational Medicine

Neurogenetic and Muscular Disorders ResearchRNA Interference and Gene Delivery

Cited by 14