Kontoravdi, Cleo

A dynamic mathematical model for monoclonal antibody N-linked glycosylation and nucleotide sugar donor transport within a maturing Golgi apparatus

Jimenez del Val, I., Nagy, J. M., & Kontoravdi, C. (2011) · Biotechnology Progress

Viral Infectious Diseases and Gene Expression in InsectsGlycosylation and Glycoproteins Research

Cited by 135

How does mild hypothermia affect monoclonal antibody glycosylation?

Sou, S. N., Sellick, C., Lee, K., Mason, A., Kyriakopoulos, S., Polizzi, K. M., & Kontoravdi, C. (2015) · Biotechnology and Bioengineering

Viral Infectious Diseases and Gene Expression in InsectsGlycosylation and Glycoproteins Research

Cited by 107

Rapid development and deployment of high‐volume vaccines for pandemic response

Kis, Z., Kontoravdi, C., Dey, A. K., Shattock, R., & Shah, N. (2020) · Journal of Advanced Manufacturing and Processing

SARS-CoV-2 and COVID-19 ResearchViral Infectious Diseases and Gene Expression in Insects

Cited by 105

Model-based optimization of antibody galactosylation in CHO cell culture

Kotidis, P., Jedrzejewski, P., Sou, S. N., Sellick, C., Polizzi, K., del Val, I. J., & Kontoravdi, C. (2019) · Biotechnology and Bioengineering

Viral Infectious Diseases and Gene Expression in InsectsProtein purification and stability

Cited by 90

Application of Global Sensitivity Analysis to Determine Goals for Design of Experiments: An Example Study on Antibody-Producing Cell Cultures

Kontoravdi, C., Asprey, S. P., Pistikopoulos, E. N., & Mantalaris, A. (2008) · Biotechnology Progress

Optimal Experimental Design MethodsProbabilistic and Robust Engineering Design

Cited by 85

Towards controlling the glycoform: A model framework linking extracellular metabolites to antibody glycosylation

Jedrzejewski, P., Del Val, I., Constantinou, A., Dell, A., Haslam, S., Polizzi, K., & Kontoravdi, C. (2014) · International Journal of Molecular Sciences

Viral Infectious Diseases and Gene Expression in InsectsGlycosylation and Glycoproteins Research

Cited by 83

Engineering Challenges in Therapeutic Protein Product and Process Design

Papathanasiou, M. M., & Kontoravdi, C. (2020) · Current Opinion in Chemical Engineering

Protein purification and stabilityViral Infectious Diseases and Gene Expression in Insects

Cited by 57

Model‐based investigation of intracellular processes determining antibody Fc‐glycosylation under mild hypothermia

Sou, S. N., Jedrzejewski, P. M., Lee, K., Sellick, C., Polizzi, K. M., & Kontoravdi, C. (2017) · Biotechnology and Bioengineering

Viral Infectious Diseases and Gene Expression in InsectsGlycosylation and Glycoproteins Research

Cited by 45

An optimized method for extraction and quantification of nucleotides and nucleotide sugars from mammalian cells

del Val, I. J., Kyriakopoulos, S., Polizzi, K. M., & Kontoravdi, C. (2013) · Analytical Biochemistry

Glycosylation and Glycoproteins ResearchViral Infectious Diseases and Gene Expression in Insects

Cited by 45

Synergising stoichiometric modelling with artificial neural networks to predict antibody glycosylation patterns in Chinese hamster ovary cells

Antonakoudis, A., Strain, B., Barbosa, R., Jimenez del Val, I., & Kontoravdi, C. (2021) · Computers & Chemical Engineering

Viral Infectious Diseases and Gene Expression in InsectsMicrobial Metabolic Engineering and Bioproduction

Cited by 42

A theoretical estimate for nucleotide sugar demand towards Chinese Hamster Ovary cellular glycosylation

del Val, I. J., Polizzi, K. M., & Kontoravdi, C. (2016) · Scientific Reports

Viral Infectious Diseases and Gene Expression in InsectsGlycosylation and Glycoproteins Research

Cited by 41

Constrained global sensitivity analysis for bioprocess design space identification

Kotidis, P., Demis, P., Goey, C. H., Correa, E., McIntosh, C., Trepekli, S., Shah, N., Klymenko, O. V., & Kontoravdi, C. (2019) · Computers & Chemical Engineering

Viral Infectious Diseases and Gene Expression in InsectsOptimal Experimental Design Methods

Cited by 40

Cascading effect in bioprocessing—The impact of mild hypothermia on CHO cell behavior and host cell protein composition

Goey, C. H., Tsang, J. M. H., Bell, D., & Kontoravdi, C. (2017) · Biotechnology and Bioengineering

Viral Infectious Diseases and Gene Expression in InsectsProtein purification and stability

Cited by 39

Glycoengineering Chinese hamster ovary cells: a short history

Donini, R., Haslam, S. M., & Kontoravdi, C. (2021) · Biochemical Society Transactions

Viral Infectious Diseases and Gene Expression in InsectsGlycosylation and Glycoproteins Research

Cited by 37

Computational tools for predicting and controlling the glycosylation of biopharmaceuticals

Kontoravdi, C., & Jimenez del Val, I. (2018) · Current Opinion in Chemical Engineering

Viral Infectious Diseases and Gene Expression in InsectsGlycosylation and Glycoproteins Research

Cited by 18

Soft sensing of intracellular states for CHO cell bioprocessing with Ensemble Kalman Filters

Yu, L., del Rio Chanona, A., & Kontoravdi, C. (2026) · Journal of Process Control

Viral Infectious Diseases and Gene Expression in InsectsControl Systems and Identification

Cited by 0