Guan, Yukun

Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy

Lv, M., Chen, M., Zhang, R., Zhang, W., Wang, C., Zhang, Y., Wei, X., Guan, Y., Liu, J., Feng, K., et al. (2020) · Cell Research

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 1,040

Manganese Increases the Sensitivity of the cGAS-STING Pathway for Double-Stranded DNA and Is Required for the Host Defense against DNA Viruses

Wang, C., Guan, Y., Lv, M., Zhang, R., Guo, Z., Wei, X., Du, X., Yang, J., Li, T., Wan, Y., et al. (2018) · Immunity

interferon and immune responsesImmune Response and Inflammation

Cited by 869

Monocyte-derived macrophages orchestrate multiple cell-type interactions to repair necrotic liver lesions in disease models

Feng, D., Xiang, X., Guan, Y., Guillot, A., Lu, H., Chang, C., He, Y., Wang, H., Pan, H., Ju, C., et al. (2023) · Journal of Clinical Investigation

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 93

Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure

Ma, J., Guillot, A., Yang, Z., Mackowiak, B., Hwang, S., Park, O., Peiffer, B. J., Ahmadi, A. R., Melo, L., Kusumanchi, P., et al. (2022) · Journal of Clinical Investigation

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 90

IL-8+ neutrophils drive inexorable inflammation in severe alcohol-associated hepatitis

Guan, Y., Peiffer, B., Feng, D., Parra, M. A., Wang, Y., Fu, Y., Shah, V. H., Cameron, A. M., Sun, Z., & Gao, B. (2024) · Journal of Clinical Investigation

Alcohol Consumption and Health EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 59

E-Selectin-Dependent Inflammation and Lipolysis in Adipose Tissue Exacerbate Steatosis-to-NASH Progression via S100A8/9

Rodrigues, R. M., He, Y., Hwang, S., Bertola, A., Mackowiak, B., Ahmed, Y. A., Seo, W., Ma, J., Wang, X., Park, S. H., et al. (2022) · Cellular and Molecular Gastroenterology and Hepatology

Liver Disease Diagnosis and TreatmentAdipokines, Inflammation, and Metabolic Diseases

Cited by 51

Inhibition of lung tumor growth by targeting EGFR/VEGFR-Akt/NF-κB pathways with novel theanine derivatives

Zhang, G., Ye, X., Ji, D., Zhang, H., Sun, F., Shang, C., Zhang, Y., Wu, E., Wang, F., Wu, F., et al. (2014) · Oncotarget

Lung Cancer Treatments and MutationsHeterocyclic Compound Synthesis and Bioactivity

Cited by 47

Inflammation in Alcohol-Associated Hepatitis: Pathogenesis and Therapeutic Targets

Feng, D., Hwang, S., Guillot, A., Wang, Y., Guan, Y., Chen, C., Maccioni, L., & Gao, B. (2024) · Cellular and Molecular Gastroenterology and Hepatology

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 44

Infiltrating macrophages replace Kupffer cells and play diverse roles in severe alcohol-associated hepatitis

Wang, Y., Guan, Y., Feng, D., Maccioni, L., Parra, M. A., Peiffer, B., Mackowiak, B., Kuwabara, T., Mori, K., Mukoyama, M., et al. (2025) · Cellular & Molecular Immunology

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 23

New therapeutic target for alcohol-associated hepatitis (AH): AH-associated IL-8+ neutrophils

Guan, Y., Feng, D., Maccioni, L., Wang, Y., & Gao, B. (2024) · eGastroenterology

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 21