Annunziato, Stefano

Mining the CRBN target space redefines rules for molecular glue-induced neosubstrate recognition

Petzold, G., Gainza, P., Annunziato, S., Lamberto, I., Trenh, P., McAllister, L. A., DeMarco, B., Schwander, L., Bunker, R. D., Zlotosch, M., et al. (2025) · Science

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 117

Mining the CRBN Target Space Redefines Rules for Molecular Glue-induced Neosubstrate Recognition

Petzold, G., Gainza, P., Annunziato, S., Lamberto, I., Trenh, P., McAllister, L., Demarco, B., Schwander, L., Bunker, R. D., Zlotosch, M., et al. (2024) · Science

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 117

ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation

Sun, T., Annunziato, S., Bergling, S., Sheng, C., Orsini, V., Forcella, P., Pikiolek, M., Kancherla, V., Holwerda, S., Imanci, D., et al. (2021) · Cell Stem Cell

Wnt/β-catenin signaling in development and cancerLiver physiology and pathology

Cited by 84

The RSPO‐LGR4/5‐ZNRF3/RNF43 module in liver homeostasis, regeneration, and disease

Annunziato, S., Sun, T., & Tchorz, J. S. (2022) · Hepatology

Wnt/β-catenin signaling in development and cancerLiver physiology and pathology

Cited by 45

Loss of Hepatic Leucine-Rich Repeat-Containing G-Protein Coupled Receptors 4 and 5 Promotes Nonalcoholic Fatty Liver Disease

Saponara, E., Penno, C., Orsini, V., Wang, Z.-Y., Fischer, A., Aebi, A., Matadamas-Guzman, M. L., Brun, V., Fischer, B., Brousseau, M., et al. (2023) · The American Journal of Pathology

Liver Disease Diagnosis and TreatmentWnt/β-catenin signaling in development and cancer

Cited by 22

Lentiviral Vector-based Insertional Mutagenesis Identifies Genes Involved in the Resistance to Targeted Anticancer Therapies

Ranzani, M., Annunziato, S., Calabria, A., Brasca, S., Benedicenti, F., Gallina, P., Naldini, L., & Montini, E. (2014) · Molecular Therapy

Virus-based gene therapy researchLung Cancer Treatments and Mutations

Cited by 17

Cereblon induces G3BP2 neosubstrate degradation using molecular surface mimicry

Annunziato, S., Quan, C., Donckele, E. J., Lamberto, I., Bunker, R. D., Zlotosch, M., Schwander, L., Murthy, A., Wiedmer, L., Staehly, C., et al. (2026) · Nature Structural & Molecular Biology

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 9

Prometheus revisited: liver homeostasis and repair

Sun, T., Annunziato, S., & Tchorz, J. S. (2020) · Aging

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 6