Birtwistle, Marc R.

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., et al. (2018) · Cell Systems

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

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Critical Role of Histone Turnover in Neuronal Transcription and Plasticity

Maze, I., Wenderski, W., Noh, K.-M., Bagot, R. C., Tzavaras, N., Purushothaman, I., Elsässer, S. J., Guo, Y., Ionete, C., Hurd, Y. L., et al. (2015) · Neuron

Genomics and Chromatin DynamicsNeuroscience and Neuropharmacology Research

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A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

Niepel, M., Hafner, M., Mills, C. E., Subramanian, K., Williams, E. H., Chung, M., Gaudio, B., Barrette, A. M., Stern, A. D., Hu, B., et al. (2019) · Cell Systems

Scientific Computing and Data ManagementAnimal testing and alternatives

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An Integrated Mechanistic Model of Pan-Cancer Driver Pathways Predicts Stochastic Proliferation and Death

Bouhaddou, M., Barrette, A. M., Koch, R. J., DiStefano, M. S., Riesel, E. A., Stern, A. D., Santos, L. C., Tan, A., Mertz, A., & Birtwistle, M. R. (2017) · PLoS Computational Biology

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

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A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens

Bouhaddou, M., Barrette, A. M., Stern, A. D., Koch, R. J., DiStefano, M. S., Riesel, E. A., Santos, L. C., Tan, A. L., Mertz, A. E., & Birtwistle, M. R. (2018) · PLOS Computational Biology

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

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A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals

Schaniel, C., Dhanan, P., Hu, B., Xiong, Y., Raghunandan, T., Gonzalez, D. M., Dariolli, R., D'Souza, S. L., Yadaw, A. S., Hansen, J., et al. (2021) · Stem Cell Reports

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

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