Hemann, Michael T.

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

Hemann, M. T., Strong, M. A., Hao, L.-Y., & Greider, C. W. (2001) · Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,219

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control

Hernando, E., Nahlé, Z., Juan, G., Diaz-Rodriguez, E., Alaminos, M., Hemann, M., Michel, L., Mittal, V., Gerald, W., Benezra, R., et al. (2004) · Nature

Microtubule and mitosis dynamicsCancer-related Molecular Pathways

Cited by 562

DNA Damage-Mediated Induction of a Chemoresistant Niche

Gilbert, L. A., & Hemann, M. T. (2010) · Cell

Lymphoma Diagnosis and TreatmentCancer Cells and Metastasis

Cited by 428

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

Miller, T. E., Liau, B. B., Wallace, L. C., Morton, A. R., Xie, Q., Dixit, D., Factor, D. C., Kim, L. J. Y., Morrow, J. J., Wu, Q., et al. (2017) · Nature

Glioma Diagnosis and TreatmentChromatin Remodeling and Cancer

Cited by 200

A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy

Wojtaszek, J. L., Chatterjee, N., Najeeb, J., Ramos, A., Lee, M., Bian, K., Xue, J. Y., Fenton, B. A., Park, H., Li, D., et al. (2019) · Cell

DNA Repair MechanismsCancer therapeutics and mechanisms

Cited by 194

Suppression of Rev3, the catalytic subunit of Polζ, sensitizes drug-resistant lung tumors to chemotherapy

Doles, J., Oliver, T. G., Cameron, E. R., Hsu, G., Jacks, T., Walker, G. C., & Hemann, M. T. (2010) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsMetal complexes synthesis and properties

Cited by 190

A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses.

Bent, E. H., Gilbert, L. A., & Hemann, M. T. (2016) · Genes & Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 179

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning

Bruno, P. M., Lu, M., Dennis, K. A., Inam, H., Moore, C. J., Sheehe, J., Elledge, S. J., Hemann, M. T., & Pritchard, J. R. (2020) · Proceedings of the National Academy of Sciences

Cancer therapeutics and mechanismsBioactive Compounds and Antitumor Agents

Cited by 175

Telomere Dysfunction Triggers Developmentally Regulated Germ Cell Apoptosis

Hemann, M. T., Rudolph, K. L., Strong, M. A., DePinho, R. A., Chin, L., & Greider, C. W. (2001) · Molecular Biology of the Cell

Telomeres, Telomerase, and SenescenceMicrotubule and mitosis dynamics

Cited by 162

Deoxycytidine release from pancreatic stellate cells promotes gemcitabine resistance

Dalin, S., Sullivan, M. R., Lau, A. N., Grauman-Boss, B., Mueller, H. S., Kreidl, E., Fenoglio, S., Luengo, A., Lees, J. A., Vander Heiden, M. G., et al. (2019) · Cancer Research

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 156

Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?

Yamanaka, K., Chatterjee, N., Hemann, M. T., & Walker, G. C. (2017) · PLOS Genetics

DNA Repair MechanismsCancer therapeutics and mechanisms

Cited by 87