Chovanec, Jack

Heritable risk for severe anaphylaxis associated with increased α-tryptase–encoding germline copy number at TPSAB1

Lyons, J. J., Chovanec, J., O’Connell, M. P., Liu, Y., Šelb, J., Zanotti, R., Bai, Y., Kim, J., Le, Q. T., DiMaggio, T., et al. (2021) · Journal of Allergy and Clinical Immunology

Mast cells and histamineFood Allergy and Anaphylaxis Research

Cited by 230

Defining baseline variability of serum tryptase levels improves accuracy in identifying anaphylaxis

Mateja, A., Wang, Q., Chovanec, J., Kim, J., Wilson, K. J., Schwartz, L. B., Glover, S. C., Carter, M. C., Metcalfe, D. D., Brittain, E., et al. (2022) · Journal of Allergy and Clinical Immunology

Mast cells and histamineFood Allergy and Anaphylaxis Research

Cited by 91

First Identification of an Inherited TPSAB1 Quintuplication in a Patient with Clonal Mast Cell Disease

Sabato, V., Chovanec, J., Faber, M., Milner, J. D., Ebo, D., & Lyons, J. J. (2018) · Journal of Clinical Immunology

Mast cells and histamineImmunodeficiency and Autoimmune Disorders

Cited by 73

Genetically defined individual reference ranges for tryptase limit unnecessary procedures and unmask myeloid neoplasms

Chovanec, J., Tunc, I., Hughes, J., Halstead, J., Mateja, A., Liu, Y., O’Connell, M. P., Kim, J., Park, Y. H., Wang, Q., et al. (2023) · Blood Advances

Mast cells and histamineGenomics and Rare Diseases

Cited by 62

A common haplotype containing functional CACNA1H variants is frequently coinherited with increased TPSAB1 copy number

Lyons, J. J., Stotz, S. C., Chovanec, J., Liu, Y., Lewis, K. L., Nelson, C., DiMaggio, T., Jones, N., Stone, K. D., Sung, H., et al. (2018) · Genetics in Medicine

Ion channel regulation and functionGenetic Associations and Epidemiology

Cited by 30

TPSAB1 genotype and effects of pro-tryptases on human mast cell–associated disorders

Lyons, J., Chovanec, J., Liu, Y., Le, Q. T., Bai, Y., Hsu, A. P., Komarow, H. D., Carter, M. C., Schwartz, L. B., Metcalfe, D. D., et al. (2017) · Journal of Allergy and Clinical Immunology

Mast cells and histamineAsthma and respiratory diseases

Cited by 2