Tomita, Taisuke

High performance plasma amyloid-β biomarkers for Alzheimer's disease

Nakamura, A., Kaneko, N., Villemagne, V. L., Kato, T., Doecke, J., Doré, V., Fowler, C., Li, Q.-X., Martins, R., Rowe, C., et al. (2018) · Nature

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,681

APP Processing and Synaptic Function

Kamenetz, F., Tomita, T., Hsieh, H., Seabrook, G., Borchelt, D., Iwatsubo, T., Sisodia, S., & Malinow, R. (2003) · Neuron

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 1,644

AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss

Hsieh, H., Boehm, J., Sato, C., Iwatsubo, T., Tomita, T., Sisodia, S., & Malinow, R. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 1,042

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein

Tu, P., Galvin, J. E., Baba, M., Giasson, B., Tomita, T., Leight, S., Nakajo, S., Iwatsubo, T., Trojanowski, J. Q., & Lee, V. M. ‐. (1998) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 686

Effects of PS1 Deficiency on Membrane Protein Trafficking in Neurons

Naruse, S., Thinakaran, G., Luo, J.-J., Kusiak, J. W., Tomita, T., Iwatsubo, T., Qian, X., Ginty, D. D., Price, D. L., Borchelt, D. R., et al. (1998) · Neuron

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 355

Mouse Models of Alzheimer’s Disease

Yokoyama, M., Kobayashi, H., Tatsumi, L., & Tomita, T. (2022) · Frontiers in Molecular Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 213

Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy

Lövestam, S., Schweighauser, M., Matsubara, T., Murayama, S., Tomita, T., Ando, T., Hasegawa, K., Yoshida, M., Tarutani, A., Hasegawa, M., et al. (2021) · FEBS Open Bio

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 183

BACE1 activity is modulated by cell-associated sphingosine-1-phosphate

Takasugi, N., Sasaki, T., Suzuki, K., Osawa, S., Isshiki, H., Hori, Y., Shimada, N., Higo, T., Yokoshima, S., Fukuyama, T., et al. (2011) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsSphingolipid Metabolism and Signaling

Cited by 181

BIN1 regulates BACE1 intracellular trafficking and amyloid-β production

Miyagawa, T., Ebinuma, I., Morohashi, Y., Hori, Y., Young Chang, M., Hattori, H., Maehara, T., Yokoshima, S., Fukuyama, T., Tsuji, S., et al. (2016) · Human Molecular Genetics

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 95

FTY720/fingolimod, a sphingosine analogue, reduces amyloid-β production in neurons

Takasugi, N., Sasaki, T., Ebinuma, I., Osawa, S., Isshiki, H., Takeo, K., Tomita, T., & Iwatsubo, T. (2013) · PLoS ONE

Alzheimer's disease research and treatmentsSphingolipid Metabolism and Signaling

Cited by 85

Molecular mechanism of intramembrane proteolysis by γ-secretase

Tomita, T. (2014) · The Journal of Biochemistry

Alzheimer's disease research and treatmentsProtease and Inhibitor Mechanisms

Cited by 58

Molecular mechanisms of the genetic risk factors in pathogenesis of Alzheimer disease

Tomita, T. (2017) · Frontiers in Bioscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 48

Genetic risk factors for Alzheimer disease: emerging roles of microglia in disease pathomechanisms

Takatori, S., Wang, W., Iguchi, A., & Tomita, T. (2019) · Advances in Experimental Medicine and Biology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 44

INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model

Iguchi, A., Takatori, S., Kimura, S., Muneto, H., Wang, K., Etani, H., Ito, G., Sato, H., Hori, Y., Sasaki, J., et al. (2023) · iScience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 37