Saur, Dieter

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase

Ruess, D. A., Heynen, G. J., Ciecielski, K. J., Ai, J., Berninger, A., Kabacaoglu, D., Görgülü, K., Dantes, Z., Wörmann, S. M., Diakopoulos, K. N., et al. (2018) · Nature Medicine

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

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Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

Eser, S., Reiff, N., Messer, M., Seidler, B., Gottschalk, K., Dobler, M., Hieber, M., Arbeiter, A., Klein, S., Kong, B., et al. (2013) · Cancer Cell

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Cell-Type-Specific Circuit Connectivity of Hippocampal CA1 Revealed through Cre-Dependent Rabies Tracing

Sun, Y., Nguyen, A. Q., Nguyen, J. P., Le, L., Saur, D., Choi, J., Callaway, E. M., & Xu, X. (2014) · Cell Reports

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

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Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body

Pan, C., Schoppe, O., Parra-Damas, A., Cai, R., Todorov, M. I., Gondi, G., von Neubeck, B., Böğürcü-Seidel, N., Seidel, S., Sleiman, K., et al. (2019) · Cell

Cell Image Analysis TechniquesAI in cancer detection

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Clonal production and organization of inhibitory interneurons in the neocortex

Brown, K. N., Chen, S., Han, Z., Lu, C.-H., Tan, X., Zhang, X.-J., Ding, L., Lopez-Cruz, A., Saur, D., Anderson, S. A., et al. (2011) · Science

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

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Cross talk between stimulated NF-κB and the tumor suppressor p53

Schneider, G., Henrich, A., Greiner, G., Wolf, V, Lovas, A., Wieczorek, M., Wagner, T., Reichardt, S., von Werder, A., Schmid, R. M., et al. (2010) · Oncogene

NF-κB Signaling PathwaysCancer-related Molecular Pathways

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Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

Zhang, H., Fillmore Brainson, C., Koyama, S., Redig, A. J., Chen, T., Li, S., Gupta, M., Garcia-de-Alba, C., Paschini, M., Herter-Sprie, G. S., et al. (2017) · Nature Communications

Epigenetics and DNA MethylationCancer Cells and Metastasis

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RORβ Spinal Interneurons Gate Sensory Transmission during Locomotion to Secure a Fluid Walking Gait

Koch, S. C., Del Barrio, M. G., Dalet, A., Gatto, G., Günther, T., Zhang, J., Seidler, B., Saur, D., Schüle, R., & Goulding, M. (2017) · Neuron

Motor Control and AdaptationNeuroscience and Neuropharmacology Research

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A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer

Lier, S., Sellmer, A., Orben, F., Heinzlmeir, S., Krauß, L., Schneeweis, C., Hassan, Z., Schneider, C., Patricia Gloria Schäfer, A., Pongratz, H., et al. (2022) · Bioorganic Chemistry

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Mdm2 inhibitors synergize with topoisomerase II inhibitors to induce p53-independent pancreatic cancer cell death

Conradt, L., Henrich, A., Wirth, M., Reichert, M., Lesina, M., Algül, H., Schmid, R. M., Krämer, O. H., Saur, D., & Schneider, G. (2013) · International Journal of Cancer

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Breaking down KRAS: Small-molecule degraders for cancer therapy

Kos, T., & Saur, D. (2025) · Signal Transduction and Targeted Therapy

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Image Analysis: Understanding and Mitigating Batch Effects in Histopathology

Gindra, R. H., Boushehri, S. S., Wagner, S. J., Tran, M., Winter, D. J. E., Schnabel, J. A., Saur, D., Marr, C., & Peng, T. (2025) · Trillium Pathology

AI in cancer detectionArtificial Intelligence in Healthcare and Education

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