Finck, Brian N.

PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis

Leone, T. C., Lehman, J. J., Finck, B. N., Schaeffer, P. J., Wende, A. R., Boudina, S., Courtois, M., Wozniak, D. F., Sambandam, N., Bernal-Mizrachi, C., et al. (2005) · PLoS Biology

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 951

FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Potthoff, M. J., Inagaki, T., Satapati, S., Ding, X., He, T., Goetz, R., Mohammadi, M., Finck, B. N., Mangelsdorf, D. J., Kliewer, S. A., et al. (2009) · Proceedings of the National Academy of Sciences

Fibroblast Growth Factor ResearchPeroxisome Proliferator-Activated Receptors

Cited by 704

A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content

Finck, B. N., Han, X., Courtois, M., Aimond, F., Nerbonne, J. M., Kovacs, A., Gross, R. W., & Kelly, D. P. (2003) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsCardiovascular Function and Risk Factors

Cited by 501

Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction

Kirk, E., Reeds, D. N., Finck, B. N., Mayurranjan, M. S., Patterson, B. W., & Klein, S. (2009) · Gastroenterology

Diet and metabolism studiesDietary Effects on Health

Cited by 440

FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

Potthoff, M. J., Boney-Montoya, J., Choi, M., He, T., Sunny, N. E., Satapati, S., Suino-Powell, K., Xu, H. E., Gerard, R. D., Finck, B. N., et al. (2011) · Cell Metabolism

Fibroblast Growth Factor ResearchMetabolism, Diabetes, and Cancer

Cited by 431

Dynamic shifts in the composition of resident and recruited macrophages influence tissue remodeling in NASH

Daemen, S., Gainullina, A., Kalugotla, G., He, L., Chan, M. M., Beals, J. W., Liss, K. H., Klein, S., Feldstein, A. E., Finck, B. N., et al. (2021) · Cell Reports

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 378

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

DeBosch, B. J., Heitmeier, M. R., Mayer, A. L., Higgins, C. B., Crowley, J. R., Kraft, T. E., Chi, M., Newberry, E. P., Chen, Z., Finck, B. N., et al. (2016) · Science Signaling

Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer

Cited by 280

A potential link between muscle peroxisome proliferator- activated receptor-α signaling and obesity-related diabetes

Finck, B. N., Bernal-Mizrachi, C., Han, D. H., Coleman, T., Sambandam, N., LaRiviere, L. L., Holloszy, J. O., Semenkovich, C. F., & Kelly, D. P. (2005) · Cell Metabolism

Peroxisome Proliferator-Activated ReceptorsMetabolism, Diabetes, and Cancer

Cited by 270

Exercise but not diet-induced weight loss decreases skeletal muscle inflammatory gene expression in frail obese elderly persons

Lambert, C. P., Wright, N. R., Finck, B. N., & Villareal, D. T. (2008) · Journal of Applied Physiology

Exercise and Physiological ResponsesNutrition and Health in Aging

Cited by 249

CD36 Deficiency Rescues Lipotoxic Cardiomyopathy

Yang, J., Sambandam, N., Han, X., Gross, R. W., Courtois, M., Kovacs, A., Febbraio, M., Finck, B. N., & Kelly, D. P. (2007) · Circulation Research

Peroxisome Proliferator-Activated ReceptorsCardiovascular Function and Risk Factors

Cited by 246

Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)—relationship to newly identified mitochondrial pyruvate carrier proteins

Colca, J. R., McDonald, W. G., Cavey, G. S., Cole, S. L., Holewa, D. D., Brightwell-Conrad, A. S., Wolfe, C. L., Wheeler, J. S., Coulter, K. R., Kilkuskie, P. M., et al. (2013) · PLoS ONE

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 171

Peroxisome Proliferator-activated Receptor α (PPARα) Signaling in the Gene Regulatory Control of Energy Metabolism in the Normal and Diseased Heart

Finck, B. N., & Kelly, D. P. (2002) · Journal of Molecular and Cellular Cardiology

Peroxisome Proliferator-Activated ReceptorsCardiovascular Function and Risk Factors

Cited by 160

Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-κB

Heyen, J. R. R., Ye, S.-M., Finck, B. N., & Johnson, R. W. (2000) · Molecular Brain Research

NF-κB Signaling PathwaysNeuroinflammation and Neurodegeneration Mechanisms

Cited by 146

The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2

Gan, Z., Burkart-Hartman, E. M., Han, D.-H., Finck, B., Leone, T. C., Smith, E. Y., Ayala, J. E., Holloszy, J., & Kelly, D. P. (2011) · Genes & Development

Peroxisome Proliferator-Activated ReceptorsMetabolism, Diabetes, and Cancer

Cited by 138

Sexually dimorphic effect of aging on skeletal muscle protein synthesis

Smith, G. I., Reeds, D. N., Hall, A. M., Chambers, K. T., Finck, B. N., & Mittendorfer, B. (2012) · Biology of Sex Differences

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 105

Treating Hepatic Steatosis and Fibrosis by Modulating Mitochondrial Pyruvate Metabolism

McCommis, K. S., & Finck, B. N. (2019) · Cellular and Molecular Gastroenterology and Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 39

Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease

Chan, M. M., Daemen, S., Beals, J. W., Terekhova, M., Yang, B. Q., Fu, C. F., He, L., Park, A. C., Smith, G. I., Razani, B., et al. (2023) · JHEP Reports

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 29

Importance of Adipose Tissue NAD+ Biology in Regulating Metabolic Flexibility

Franczyk, M. P., Qi, N., Stromsdorfer, K. L., Li, C., Yamaguchi, S., Itoh, H., Yoshino, M., Sasaki, Y., Brookheart, R. T., Finck, B. N., et al. (2021) · Endocrinology

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 23