Arvedson, Tara

The Clinical KRAS(G12C) Inhibitor AMG 510 Drives Anti-Tumour Immunity

Canon, J., Rex, K., Saiki, A. Y., Mohr, C., Cooke, K., Bagal, D., Gaida, K., Holt, T., Knutson, C. G., Koppada, N., et al. (2019) · Nature

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

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On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Theurl, I., Hilgendorf, I., Nairz, M., Tymoszuk, P., Haschka, D., Asshoff, M., He, S., Gerhardt, L. M. S., Holderried, T. A. W., Seifert, M., et al. (2016) · Nature Medicine

Phagocytosis and Immune RegulationIron Metabolism and Disorders

Cited by 412

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

Billesbølle, C. B., Azumaya, C. M., Kretsch, R. C., Powers, A. S., Gonen, S., Schneider, S., Arvedson, T., Dror, R. O., Cheng, Y., & Manglik, A. (2020) · Nature

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 344

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

Sasu, B. J., Cooke, K. S., Arvedson, T. L., Plewa, C., Ellison, A. R., Sheng, J., Winters, A., Juan, T., Li, H., Begley, C. G., et al. (2010) · Blood

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 251

Hepcidin Revisited, Disulfide Connectivity, Dynamics, and Structure

Jordan, J. B., Poppe, L., Haniu, M., Arvedson, T., Syed, R., Li, V., Kohno, H., Kim, H., Schnier, P. D., Harvey, T. S., et al. (2009) · Journal of Biological Chemistry

Iron Metabolism and DisordersProtein Structure and Dynamics

Cited by 214

Hepcidin regulation in prostate and its disruption in prostate cancer

Tesfay, L., Clausen, K. A., Kim, J. W., Hegde, P., Wang, X., Miller, L. D., Deng, Z., Blanchette, N., Arvedson, T., Miranti, C. K., et al. (2015) · Cancer Research

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 186

Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT

Ross, S. L., Tran, L., Winters, A., Lee, K.-J., Plewa, C., Foltz, I., King, C., Miranda, L. P., Allen, J., Beckman, H., et al. (2012) · Cell Metabolism

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 145

Dendritic cell–derived hepcidin sequesters iron from the microbiota to promote mucosal healing

Bessman, N. J., Mathieu, J. R. R., Renassia, C., Zhou, L., Fung, T. C., Fernandez, K. C., Austin, C., Moeller, J. B., Zumerle, S., Louis, S., et al. (2020) · Science

Iron Metabolism and DisordersInflammatory Bowel Disease

Cited by 145

Discovery of N-(1-Acryloylazetidin-3-yl)-2-(1 H-indol-1-yl)acetamides as Covalent Inhibitors of KRASG12C

Shin, Y., Jeong, J. W., Wurz, R. P., Achanta, P., Arvedson, T., Bartberger, M. D., Campuzano, I. D. G., Fucini, R., Hansen, S. K., Ingersoll, J., et al. (2019) · ACS Medicinal Chemistry Letters

Protein Kinase Regulation and GTPase SignalingHeterocyclic Compound Synthesis and Bioactivity

Cited by 113

Serum hepcidin but not prohepcidin may be an effective marker for anemia of inflammation (AI)

Sasu, B. J., Li, H., Rose, M. J., Arvedson, T. L., Doellgast, G., & Molineux, G. (2010) · Blood Cells Molecules and Diseases

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 43

Classical and intermediate monocytes scavenge non-transferrin-bound iron and damaged erythrocytes

Haschka, D., Petzer, V., Kocher, F., Tschurtschenthaler, C., Schaefer, B., Seifert, M., Sopper, S., Sonnweber, T., Feistritzer, C., Arvedson, T. L., et al. (2019) · JCI Insight

Iron Metabolism and DisordersPhagocytosis and Immune Regulation

Cited by 34

Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

Ross, S. L., Biswas, K., Rottman, J., Allen, J. R., Long, J., Miranda, L. P., Winters, A., & Arvedson, T. L. (2017) · Frontiers in Pharmacology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 33