Melnyk, Stepan

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism

James, S. J., Cutler, P., Melnyk, S., Jernigan, S., Janak, L., Gaylor, D. W., & Neubrander, J. A. (2004) · The American Journal of Clinical Nutrition

Autism Spectrum Disorder ResearchFolate and B Vitamins Research

Cited by 955

Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain

Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E., & James, S. J. (2012) · Translational Psychiatry

Autism Spectrum Disorder ResearchRedox biology and oxidative stress

Cited by 480

Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism

Melnyk, S., Fuchs, G. J., Schulz, E., Lopez, M., Kahler, S. G., Fussell, J. J., Bellando, J., Pavliv, O., Rose, S., Seidel, L., et al. (2012) · Journal of Autism and Developmental Disorders

Autism Spectrum Disorder ResearchEpigenetics and DNA Methylation

Cited by 250

Oxidative Stress Induces Mitochondrial Dysfunction in a Subset of Autism Lymphoblastoid Cell Lines in a Well-Matched Case Control Cohort

Rose, S., Frye, R. E., Slattery, J., Wynne, R., Tippett, M., Pavliv, O., Melnyk, S., & James, S. J. (2014) · PLoS ONE

Mitochondrial Function and PathologyAutism Spectrum Disorder Research

Cited by 168

Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines

Frye, R. E., Rose, S., Chacko, J., Wynne, R., Bennuri, S. C., Slattery, J. C., Tippett, M., Delhey, L., Melnyk, S., Kahler, S. G., et al. (2016) · Translational Psychiatry

Gut microbiota and healthAutism Spectrum Disorder Research

Cited by 130

Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum

James, S. J., Shpyleva, S., Melnyk, S., Pavliv, O., & Pogribny, I. P. (2013) · Translational Psychiatry

Autism Spectrum Disorder ResearchEpigenetics and DNA Methylation

Cited by 100

Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum

Shpyleva, S., Ivanovsky, S., de Conti, A., Melnyk, S., Tryndyak, V., Beland, F. A., James, S. J., & Pogribny, I. P. (2014) · PLoS ONE

Autism Spectrum Disorder ResearchEpigenetics and DNA Methylation

Cited by 83

Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum

James, S. J., Shpyleva, S., Melnyk, S., Pavliv, O., & Pogribny, I. P. (2014) · Translational Psychiatry

Epigenetics and DNA MethylationGenetics and Neurodevelopmental Disorders

Cited by 79