Gleeson, Paul A.

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

Farg, M. A., Sundaramoorthy, V., Sultana, J. M., Yang, S., Atkinson, R. A. K., Levina, V., Halloran, M. A., Gleeson, P. A., Blair, I. P., Soo, K. Y., et al. (2014) · Human Molecular Genetics

Amyotrophic Lateral Sclerosis ResearchCellular transport and secretion

Cited by 478

Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b‐ and AP4‐dependent pathway

Toh, W. H., Tan, J. Z. A., Zulkefli, K. L., Houghton, F. J., & Gleeson, P. A. (2017) · Traffic

Cellular transport and secretionAlzheimer's disease research and treatments

Cited by 75

Intracellular Itinerary of Internalised β‐Secretase, BACE1, and Its Potential Impact on β‐Amyloid Peptide Biogenesis

Chia, P. Z. C., Toh, W. H., Sharples, R., Gasnereau, I., Hill, A. F., & Gleeson, P. A. (2013) · Traffic

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 67

Dysregulation of intracellular trafficking and endosomal sorting in Alzheimer's disease: controversies and unanswered questions

Toh, W. H., & Gleeson, P. A. (2016) · Biochemical Journal

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 62

GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production

Toh, W. H., Chia, P. Z. C., Hossain, M. I., & Gleeson, P. A. (2018) · Molecular Biology of the Cell

Cellular transport and secretionAlzheimer's disease research and treatments

Cited by 61

Recycling endosome-dependent and -independent mechanisms for IL-10 secretion in LPS-activated macrophages

Stanley, A. C., Lieu, Z. Z., Wall, A. A., Venturato, J., Khromykh, T., Hamilton, N. A., Gleeson, P. A., & Stow, J. L. (2012) · Journal of Leukocyte Biology

Cellular transport and secretionImmune Response and Inflammation

Cited by 55

A role for Rab11 in the homeostasis of the endosome-lysosomal pathway

Zulkefli, K. L., Houghton, F. J., Gosavi, P., & Gleeson, P. A. (2019) · Experimental Cell Research

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 52

Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-β production

Tan, J. Z. A., Fourriere, L., Wang, J., Perez, F., Boncompain, G., & Gleeson, P. A. (2020) · Molecular Biology of the Cell

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 37