Wagner, Gerhard

Identification of RIP1 kinase as a specific cellular target of necrostatins

Degterev, A., Hitomi, J., Germscheid, M., Ch'en, I. L., Korkina, O., Teng, X., Abbott, D., Cuny, G. D., Yuan, C., Wagner, G., et al. (2008) · Nature Chemical Biology

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 2,059

Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix

Walensky, L. D., Kung, A. L., Escher, I., Malia, T. J., Barbuto, S., Wright, R. D., Wagner, G., Verdine, G. L., & Korsmeyer, S. J. (2004) · Science

Cell death mechanisms and regulationChemical Synthesis and Analysis

Cited by 1,349

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

Locasale, J. W., Grassian, A. R., Melman, T., Lyssiotis, C. A., Mattaini, K. R., Bass, A. J., Heffron, G., Metallo, C. M., Muranen, T., Sharfi, H., et al. (2011) · Nature Genetics

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 1,120

Solution structure of the integral human membrane protein VDAC-1 in detergent micelles

Hiller, S., Garces, R. G., Malia, T. J., Orekhov, V. Y., Colombini, M., & Wagner, G. (2008) · Science

Protein Structure and DynamicsLipid Membrane Structure and Behavior

Cited by 667

An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis

Yang, F., Vought, B. W., Satterlee, J. S., Walker, A. K., Jim Sun, Z.-Y., Watts, J. L., DeBeaumont, R., Mako Saito, R., Hyberts, S. G., Yang, S., et al. (2006) · Nature

Cancer, Lipids, and MetabolismCholesterol and Lipid Metabolism

Cited by 405

A nuclear receptor-like pathway regulating multidrug resistance in fungi

Thakur, J. K., Arthanari, H., Yang, F., Pan, S.-J., Fan, X., Breger, J., Frueh, D. P., Gulshan, K., Li, D. K., Mylonakis, E., et al. (2008) · Nature

Fungal and yeast genetics researchAntifungal resistance and susceptibility

Cited by 343

Covalently circularized nanodiscs for studying membrane proteins and viral entry

Nasr, M. L., Baptista, D., Strauss, M., Sun, Z.-Y. J., Grigoriu, S., Huser, S., Plückthun, A., Hagn, F., Walz, T., Hogle, J. M., et al. (2017) · Nature Methods

Lipid Membrane Structure and BehaviorProtein Structure and Dynamics

Cited by 262

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

Cherepanov, P., Sun, Z.-Y. J., Rahman, S., Maertens, G., Wagner, G., & Engelman, A. (2005) · Nature Structural & Molecular Biology

HIV Research and TreatmentProtein Structure and Dynamics

Cited by 235

PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains

Suzuki, C., Garces, R. G., Edmonds, K. A., Hiller, S., Hyberts, S. G., Marintchev, A., & Wagner, G. (2008) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 165

Inhibiting fungal multidrug resistance by disrupting an activator–Mediator interaction

Nishikawa, J. L., Boeszoermenyi, A., Vale-Silva, L. A., Torelli, R., Posteraro, B., Sohn, Y.-J., Ji, F., Gelev, V., Sanglard, D., Sanguinetti, M., et al. (2016) · Nature

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 146

Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation

Hoeffer, C. A., Cowansage, K. K., Arnold, E. C., Banko, J. L., Moerke, N. J., Rodriguez, R., Schmidt, E. K., Klosi, E., Chorev, M., Lloyd, R. E., et al. (2011) · Proceedings of the National Academy of Sciences

Memory and Neural MechanismsMemory Processes and Influences

Cited by 114

Mediator Subunit Gal11p/MED15 Is Required for Fatty Acid-dependent Gene Activation by Yeast Transcription Factor Oaf1p

Thakur, J. K., Arthanari, H., Yang, F., Chau, K. H., Wagner, G., & Näär, A. M. (2009) · Journal of Biological Chemistry

Peroxisome Proliferator-Activated ReceptorsGenomics and Chromatin Dynamics

Cited by 96

The CD58 (LFA-3) binding site is a localized and highly charged surface area on the AGFCC'C" face of the human CD2 adhesion domain.

Arulanandam, A. R., Withka, J. M., Wyss, D. F., Wagner, G., Kister, A., Pallai, P., Recny, M. A., & Reinherz, E. L. (1993) · Proceedings of the National Academy of Sciences

Cell Adhesion Molecules ResearchT-cell and B-cell Immunology

Cited by 85

Structural Features of the αβTCR Mechanotransduction Apparatus That Promote pMHC Discrimination

Brazin, K. N., Mallis, R. J., Das, D. K., Feng, Y., Hwang, W., Wang, J.-H., Wagner, G., Lang, M. J., & Reinherz, E. L. (2015) · Frontiers in Immunology

T-cell and B-cell ImmunologyProtein Structure and Dynamics

Cited by 70

Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin

Jayaraj, A., Schwanz, H. A., Spencer, D. J., Bhasin, S., Hamilton, J. A., Jayaram, B., Goldman, A. L., Krishna, M., Krishnan, M., Shah, A., et al. (2021) · Endocrinology

Protein Interaction Studies and Fluorescence AnalysisProtein Structure and Dynamics

Cited by 28

Deep computational analysis details dysregulation of eukaryotic translation initiation complex eIF4F in human cancers

Wu, S., & Wagner, G. (2021) · Cell Systems

RNA and protein synthesis mechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 20