Switzer, Christopher H.

The chemical biology of nitric oxide: Implications in cellular signaling

Thomas, D. D., Ridnour, L. A., Isenberg, J. S., Flores-Santana, W., Switzer, C. H., Donzelli, S., Hussain, P., Vecoli, C., Paolocci, N., Ambs, S., et al. (2008) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 975

Nitric oxide and redox mechanisms in the immune response

Wink, D. A., Hines, H. B., Cheng, R. Y. S., Switzer, C. H., Flores-Santana, W., Vitek, M. P., Ridnour, L. A., & Colton, C. A. (2011) · Journal of Leukocyte Biology

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 765

Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients

Glynn, S. A., Boersma, B. J., Dorsey, T. H., Yi, M., Yfantis, H. G., Ridnour, L. A., Martin, D. N., Switzer, C. H., Hudson, R. S., Wink, D. A., et al. (2010) · Journal of Clinical Investigation

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 254

Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression

Heinecke, J. L., Ridnour, L. A., Cheng, R. Y. S., Switzer, C. H., Lizardo, M. M., Khanna, C., Glynn, S. A., Hussain, S. P., Young, H. A., Ambs, S., et al. (2014) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsImmune cells in cancer

Cited by 177

Targeting SET/I2PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy

Switzer, C. H., Cheng, R. Y. S., Vitek, T. M., Christensen, D. J., Wink, D. A., & Vitek, M. P. (2011) · Oncogene

Protein Kinase Regulation and GTPase SignalingMechanisms of cancer metastasis

Cited by 171

Signaling and stress: The redox landscape in NOS2 biology

Thomas, D. D., Heinecke, J. L., Ridnour, L. A., Cheng, R. Y., Kesarwala, A. H., Switzer, C. H., McVicar, D. W., Roberts, D. D., Glynn, S., Fukuto, J. M., et al. (2015) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 150

S-nitrosylation of EGFR and Src activates an oncogenic signaling network in human basal-like breast cancer

Switzer, C. H., Glynn, S. A., Cheng, R. Y.-S., Ridnour, L. A., Green, J. E., Ambs, S., & Wink, D. A. (2012) · Molecular Cancer Research

HER2/EGFR in Cancer ResearchNitric Oxide and Endothelin Effects

Cited by 141

Evidence against Stable Protein S-Nitrosylation as a Widespread Mechanism of Post-translational Regulation

Wolhuter, K., Whitwell, H. J., Switzer, C. H., Burgoyne, J. R., Timms, J. F., & Eaton, P. (2018) · Molecular Cell

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 111

Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-l-arginine

Donzelli, S., Espey, M. G., Flores-Santana, W., Switzer, C. H., Yeh, G. C., Huang, J., Stuehr, D. J., King, S. B., Miranda, K. M., & Wink, D. A. (2008) · Free Radical Biology and Medicine

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 91

Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer

Switzer, C. H., Cheng, R. Y.-S., Ridnour, L. A., Glynn, S. A., Ambs, S., & Wink, D. A. (2012) · Breast Cancer Research

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 91

Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer

Switzer, C. H., Glynn, S. A., Ridnour, L. A., Cheng, R. Y.-S., Vitek, M. P., Ambs, S., & Wink, D. A. (2011) · Trends in Pharmacological Sciences

Breast Cancer Treatment StudiesNitric Oxide and Endothelin Effects

Cited by 74

Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation

Ridnour, L. A., Barasch, K. M., Windhausen, A. N., Dorsey, T. H., Lizardo, M. M., Yfantis, H. G., Lee, D. H., Switzer, C. H., Cheng, R. Y. S., Heinecke, J. L., et al. (2012) · PLoS ONE

Protease and Inhibitor MechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 71

A Strategy for Origins of Life Research

Scharf, C., Virgo, N., Cleaves, H. J., Aono, M., Aubert-Kato, N., Aydinoglu, A., Barahona, A., Barge, L. M., Benner, S. A., Biehl, M., et al. (2015) · Astrobiology

Origins and Evolution of LifeSpace Science and Extraterrestrial Life

Cited by 65

Comparing the chemical biology of NO and HNO

Flores-Santana, W., Switzer, C., Ridnour, L. A., Basudhar, D., Mancardi, D., Donzelli, S., Thomas, D. D., Miranda, K. M., Fukuto, J. M., & Wink, D. A. (2009) · Archives of Pharmacal Research

Nitric Oxide and Endothelin EffectsHemoglobin structure and function

Cited by 50

Activity of 2’,5’-linked RNA in the template-directed oligomerization of mononucleotides

Prakash, T. P., Roberts, C., & Switzer, C. (1997) · Angewandte Chemie International Edition in English

Origins and Evolution of LifeRNA and protein synthesis mechanisms

Cited by 34