Chew, Emily Y.

A global reference for human genetic variation

The 1000 Genomes Project Consortium, authors, C., Auton, A., Abecasis, G. R., Steering committee, Altshuler, D. M., Durbin, R. M., Abecasis, G. R., Bentley, D. R., Chakravarti, A., et al. (2015) · Nature

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 18,247

Complement factor H polymorphism in age-related macular degeneration

Klein, R. J., Zeiss, C., Chew, E. Y., Tsai, J.-Y., Sackler, R. S., Haynes, C., Henning, A. K., SanGiovanni, J. P., Mane, S. M., Mayne, S. T., et al. (2005) · Science

Retinal Diseases and TreatmentsComplement system in diseases

Cited by 4,492

Next-generation genotype imputation service and methods

Das, S., Forer, L., Schönherr, S., Sidore, C., Locke, A. E., Kwong, A., Vrieze, S. I., Chew, E. Y., Levy, S., McGue, M., et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Phylogenetic Studies

Cited by 3,808

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Fritsche, L. G., Igl, W., Bailey, J. N. C., Grassmann, F., Sengupta, S., Bragg-Gresham, J. L., Burdon, K. P., Hebbring, S. J., Wen, C., Gorski, M., et al. (2016) · Nature Genetics

Retinal Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 1,544

Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data

Spaide, R. F., Jaffe, G. J., Sarraf, D., Freund, K. B., Sadda, S. R., Staurenghi, G., Waheed, N. K., Chakravarthy, U., Rosenfeld, P. J., Holz, F. G., et al. (2020) · Ophthalmology

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 824

Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks: Meta-analysis of 10 Trials Involving 77 917 Individuals

Aung, T., Halsey, J., Kromhout, D., Gerstein, H. C., Marchioli, R., Tavazzi, L., Geleijnse, J. M., Rauch, B., Ness, A., Galan, P., et al. (2018) · JAMA Cardiology

Fatty Acid Research and HealthNutritional Studies and Diet

Cited by 632

Age-related macular degeneration

Coleman, H. R., Chan, C.-C., Ferris, F. L., & Chew, E. Y. (2008) · The Lancet

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 542

Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration

Chen, W., Stambolian, D., Edwards, A. O., Branham, K. E., Othman, M., Jakobsdottir, J., Tosakulwong, N., Pericak-Vance, M. A., Campochiaro, P. A., Klein, M. L., et al. (2010) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 506

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Consortium for Refractive Error and Myopia (CREAM), Verhoeven, V. J. M., The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Wellcome Trust Case Control Consortium 2 (WTCCC2), The Fuchs' Genetics Multi-Center Study Group, Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Höhn, R., et al. (2013) · Nature Genetics

Ophthalmology and Visual Impairment StudiesGenetic Associations and Epidemiology

Cited by 487

Secondary Analyses of the Effects of Lutein/Zeaxanthin on Age-Related Macular Degeneration Progression: AREDS2 Report No. 3

Chew, E. Y., Clemons, T. E., SanGiovanni, J. P., Danis, R. P., Ferris, F. L., Elman, M. J., Antoszyk, A. N., Ruby, A. J., Orth, D., Bressler, S. B., et al. (2014) · JAMA Ophthalmology

Retinal Diseases and TreatmentsAntioxidant Activity and Oxidative Stress

Cited by 415

Metabolic Control and Progression of Retinopathy: The Diabetes in Early Pregnancy Study

Chew, E. Y., Mills, J. L., Metzger, B. E., Remaley, N. A., Jovanovic-Peterson, L., Knopp, R. H., Conley, M., Rand, L., Simpson, J. L., Holmes, L. B., et al. (1995) · Diabetes Care

Retinal Diseases and TreatmentsGestational Diabetes Research and Management

Cited by 402

Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration

Ratnapriya, R., Sosina, O. A., Starostik, M. R., Kwicklis, M., Kapphahn, R. J., Fritsche, L. G., Walton, A., Arvanitis, M., Gieser, L., Pietraszkiewicz, A., et al. (2019) · Nature Genetics

Retinal Diseases and TreatmentsGenetic Associations and Epidemiology

Cited by 312

Unraveling a Multifactorial Late-Onset Disease: From Genetic Susceptibility to Disease Mechanisms for Age-Related Macular Degeneration

Swaroop, A., Chew, E. Y., Bowes Rickman, C., & Abecasis, G. R. (2009) · Annual Review of Genomics and Human Genetics

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 270

Report from the NEI/FDA endpoints workshop on age-related macular degeneration and inherited retinal diseases

Csaky, K., Ferris, F., Chew, E. Y., Nair, P., Cheetham, J. K., & Duncan, J. L. (2017) · Investigative Opthalmology & Visual Science

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 231

The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration

Tuo, J., Smith, B. C., Bojanowski, C. M., Meleth, A. D., Gery, I., Csaky, K. G., Chew, E. Y., & Chan, C.-C. (2004) · The FASEB Journal

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 215

Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial

Chew, E. Y., Clemons, T. E., Agrón, E., Launer, L. J., Grodstein, F., & Bernstein, P. S. (2015) · JAMA

Fatty Acid Research and HealthDementia and Cognitive Impairment Research

Cited by 191

ω–3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study

SanGiovanni, J. P., Agrón, E., Meleth, A. D., Reed, G. F., Sperduto, R. D., Clemons, T. E., & Chew, E. Y. (2009) · The American Journal of Clinical Nutrition

Retinal Diseases and TreatmentsFatty Acid Research and Health

Cited by 186

TACHYPHYLAXIS AFTER INTRAVITREAL BEVACIZUMAB FOR EXUDATIVE AGE-RELATED MACULAR DEGENERATION

FOROOGHIAN, F., CUKRAS, C., MEYERLE, C. B., CHEW, E. Y., & WONG, W. T. (2009) · Retina

Retinal Diseases and TreatmentsOcular Diseases and Behçet’s Syndrome

Cited by 179

Natural history of drusenoid pigment epithelial detachment in age-related macular degeneration: Age-Related Eye Disease Study Report No. 28

Cukras, C., Agrón, E., Klein, M. L., Ferris, F. L., Chew, E. Y., Gensler, G., & Wong, W. T. (2010) · Ophthalmology

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 170

Hypomethylation of the IL17RC Promoter Associates with Age-Related Macular Degeneration

Wei, L., Liu, B., Tuo, J., Shen, D., Chen, P., Li, Z., Liu, X., Ni, J., Dagur, P., Sen, H. N., et al. (2012) · Cell Reports

Retinal Diseases and TreatmentsEpigenetics and DNA Methylation

Cited by 167

Complement Component C5a Promotes Expression of IL-22 and IL-17 from Human T Cells and Its Implication in Age-Related Macular Degeneration

Liu, B., Wei, L., Meyerle, C., Tuo, J., Sen, H. N., Li, Z., Chakrabarty, S., Agron, E., Chan, C.-C., Klein, M. L., et al. (2011) · Journal of Translational Medicine

Complement system in diseasesRetinal Diseases and Treatments

Cited by 164

Effect of Long-Chain ω-3 Fatty Acids and Lutein + Zeaxanthin Supplements on Cardiovascular Outcomes: Results of the Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial

Bonds, D. E., Harrington, M., Worrall, B. B., Bertoni, A. G., Eaton, C. B., Hsia, J., Robinson, J., Clemons, T. E., Fine, L. J., & Chew, E. Y. (2014) · JAMA Internal Medicine

Fatty Acid Research and HealthRetinal Diseases and Treatments

Cited by 118

Synergic effect of polymorphisms in ERCC6 5′ flanking region and complement factor H on age-related macular degeneration predisposition

Tuo, J., Ning, B., Bojanowski, C. M., Lin, Z.-N., Ross, R. J., Reed, G. F., Shen, D., Jiao, X., Zhou, M., Chew, E. Y., et al. (2006) · Proceedings of the National Academy of Sciences

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 114

Foundational Considerations for Artificial Intelligence Using Ophthalmic Images

Abràmoff, M. D., Cunningham, B., Patel, B., Eydelman, M. B., Leng, T., Sakamoto, T., Blodi, B., Grenon, S. M., Wolf, R. M., Manrai, A. K., et al. (2022) · Ophthalmology

Artificial Intelligence in Healthcare and EducationEthics and Social Impacts of AI

Cited by 96