Letterio, John J.

Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

Ashcroft, G. S., Yang, X., Glick, A. B., Weinstein, M., Letterio, J. J., Mizel, D. E., Anzano, M., Greenwell-Wild, T., Wahl, S. M., Deng, C., et al. (1999) · Nature Cell Biology

TGF-β signaling in diseasesWound Healing and Treatments

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A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans Cells

Borkowski, T. A., Letterio, J. J., Farr, A. G., & Udey, M. C. (1996) · The Journal of Experimental Medicine

T-cell and B-cell ImmunologyTGF-β signaling in diseases

Cited by 474

Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects

Yang, Y.-A., Dukhanina, O., Tang, B., Mamura, M., Letterio, J. J., MacGregor, J., Patel, S. C., Khozin, S., Liu, Z.-Y., Green, J., et al. (2002) · Journal of Clinical Investigation

TGF-β signaling in diseasesMechanisms of cancer metastasis

Cited by 404

IL-13 Activates a Mechanism of Tissue Fibrosis That Is Completely TGF-β Independent

Kaviratne, M., Hesse, M., Leusink, M., Cheever, A. W., Davies, S. J., McKerrow, J. H., Wakefield, L. M., Letterio, J. J., & Wynn, T. A. (2004) · The Journal of Immunology

Liver physiology and pathologyTGF-β signaling in diseases

Cited by 370

Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype.

Geiser, A. G., Letterio, J. J., Kulkarni, A. B., Karlsson, S., Roberts, A. B., & Sporn, M. B. (1993) · Proceedings of the National Academy of Sciences

TGF-β signaling in diseasesT-cell and B-cell Immunology

Cited by 179

Amyloid-β precursor protein promotes cell proliferation and motility of advanced breast cancer

Lim, S., Yoo, B. K., Kim, H.-S., Gilmore, H. L., Lee, Y., Lee, H.-P., Kim, S.-J., Letterio, J., & Lee, H.-G. (2014) · BMC Cancer

Alzheimer's disease research and treatmentsCancer Cells and Metastasis

Cited by 100

Hepatic Stellate Cells Inhibit T Cells through Active TGF-β1 from a Cell Surface–Bound Latent TGF-β1/GARP Complex

Li, Y., Kim, B.-G., Qian, S., Letterio, J. J., Fung, J. J., Lu, L., & Lin, F. (2015) · The Journal of Immunology

Liver physiology and pathologyTGF-β signaling in diseases

Cited by 45

Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727

Lam, E., Choi, S. H., Pareek, T. K., Kim, B.-G., & Letterio, J. J. (2015) · Molecular Immunology

T-cell and B-cell ImmunologyCytokine Signaling Pathways and Interactions

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