Neff, Frauke

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Friedmann Angeli, J. P., Schneider, M., Proneth, B., Tyurina, Y. Y., Tyurin, V. A., Hammond, V. J., Herbach, N., Aichler, M., Walch, A., Eggenhofer, E., et al. (2014) · Nature Cell Biology

Ferroptosis and cancer prognosisCell death mechanisms and regulation

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Cardioprotection and lifespan extension by the natural polyamine spermidine

Eisenberg, T., Abdellatif, M., Schroeder, S., Primessnig, U., Stekovic, S., Pendl, T., Harger, A., Schipke, J., Zimmermann, A., Schmidt, A., et al. (2016) · Nature Medicine

Polyamine Metabolism and ApplicationsGenetics, Aging, and Longevity in Model Organisms

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A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains

Simon, M. M., Greenaway, S., White, J. K., Fuchs, H., Gailus-Durner, V., Wells, S., Sorg, T., Wong, K., Bedu, E., Cartwright, E. J., et al. (2013) · Genome Biology

Genetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals

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Rapamycin extends murine lifespan but has limited effects on aging

Neff, F., Flores-Dominguez, D., Ryan, D. P., Horsch, M., Schröder, S., Adler, T., Afonso, L. C., Aguilar-Pimentel, J. A., Becker, L., Garrett, L., et al. (2013) · Journal of Clinical Investigation

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

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Prevalence of sexual dimorphism in mammalian phenotypic traits

Karp, N. A., Mason, J., Beaudet, A. L., Benjamini, Y., Bower, L., Braun, R. E., Brown, S. D. M., Chesler, E. J., Dickinson, M. E., Flenniken, A. M., et al. (2017) · Nature Communications

Sex and Gender in HealthcareGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

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Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts

Keller, J., Catala-Lehnen, P., Huebner, A. K., Jeschke, A., Heckt, T., Lueth, A., Krause, M., Koehne, T., Albers, J., Schulze, J., et al. (2014) · Nature Communications

Bone Metabolism and DiseasesSphingolipid Metabolism and Signaling

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Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

Finan, B., Clemmensen, C., Zhu, Z., Stemmer, K., Gauthier, K., Müller, L., De Angelis, M., Moreth, K., Neff, F., Perez-Tilve, D., et al. (2016) · Cell

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

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Long-Term Cold Adaptation Does Not Require FGF21 or UCP1

Keipert, S., Kutschke, M., Ost, M., Schwarzmayr, T., van Schothorst, E. M., Lamp, D., Brachthäuser, L., Hamp, I., Mazibuko, S. E., Hartwig, S., et al. (2017) · Cell Metabolism

Adipose Tissue and MetabolismFibroblast Growth Factor Research

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Monomeric GLP-1/GIP/Glucagon Triagonism Corrects Obesity, Hepatosteatosis, and Dyslipidemia in Female Mice

Jall, S., Sachs, S., Clemmensen, C., Finan, B., Neff, F., DiMarchi, R. D., Tschöp, M. H., Müller, T. D., & Hofmann, S. M. (2017) · Molecular Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

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Bezafibrate improves insulin sensitivity and metabolic flexibility in STZ-induced diabetic mice

Franko, A., Huypens, P., Neschen, S., Irmler, M., Rozman, J., Rathkolb, B., Neff, F., Prehn, C., Dubois, G., Baumann, M., et al. (2016) · Diabetes

Peroxisome Proliferator-Activated ReceptorsDiabetes Treatment and Management

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CIP2A promotes T-cell activation and immune response to Listeria monocytogenes infection

Côme, C., Cvrljevic, A., Khan, M. M., Treise, I., Adler, T., Aguilar-Pimentel, J. A., Au-Yeung, B., Sittig, E., Laajala, T. D., Chen, Y., et al. (2016) · PLoS ONE

T-cell and B-cell ImmunologySignaling Pathways in Disease

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