Liu, Tongzheng

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

Yang, Z., Shi, J., Xie, J., Wang, Y., Sun, J., Liu, T., Zhao, Y., Zhao, X., Wang, X., Ma, Y., et al. (2019) · Nature Biomedical Engineering

Extracellular vesicles in diseaseRNA Interference and Gene Delivery

Cited by 744

Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy

Zhu, B., Tang, L., Chen, S., Yin, C., Peng, S., Li, X., Liu, T., Liu, W., Han, C., Stawski, L., et al. (2018) · Oncogene

Cancer Immunotherapy and BiomarkersMelanoma and MAPK Pathways

Cited by 117

Efficient targeted oncogenic KRASG12C degradation via first reversible-covalent PROTAC

Yang, F., Wen, Y., Wang, C., Zhou, Y., Zhou, Y., Zhang, Z.-M., Liu, T., & Lu, X. (2022) · European Journal of Medicinal Chemistry

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 109

WSB1 promotes tumor metastasis by inducing pVHL degradation

Kim, J. J., Lee, S. B., Jang, J., Yi, S.-Y., Kim, S.-H., Han, S.-A., Lee, J.-M., Tong, S.-Y., Vincelette, N. D., Gao, B., et al. (2015) · Genes & Development

Cancer, Hypoxia, and MetabolismUbiquitin and proteasome pathways

Cited by 83

Regulation of SIRT1 activity by genotoxic stress

Yuan, J., Luo, K., Liu, T., & Lou, Z. (2012) · Genes & Development

Sirtuins and Resveratrol in MedicineDNA Repair Mechanisms

Cited by 79

Novel insights into stress-induced susceptibility to influenza: corticosterone impacts interferon-β responses by Mfn2-mediated ubiquitin degradation of MAVS

Luo, Z., Liu, L.-F., Jiang, Y.-N., Tang, L.-P., Li, W., Ouyang, S.-H., Tu, L.-F., Wu, Y.-P., Gong, H.-B., Yan, C.-Y., et al. (2020) · Signal Transduction and Targeted Therapy

interferon and immune responsesImmune Response and Inflammation

Cited by 34

Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells

Liu, T., Huang, Y., Likhotvorik, R. I., Keshvara, L., & Hoyt, D. G. (2008) · American Journal of Physiology-Cell Physiology

Signaling Pathways in DiseaseNitric Oxide and Endothelin Effects

Cited by 25

Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells

Liu, T., Schneider, R. A., Shah, V., Huang, Y., Likhotvorik, R. I., Keshvara, L., & Hoyt, D. G. (2009) · Journal of Inflammation

Signaling Pathways in DiseaseCalpain Protease Function and Regulation

Cited by 13