Steinkühler, Christian

HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics

Gallinari, P., Marco, S. D., Jones, P., Pallaoro, M., & Steinkühler, C. (2007) · Cell Research

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 678

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

Vannini, A., Volpari, C., Filocamo, G., Casavola, E. C., Brunetti, M., Renzoni, D., Chakravarty, P., Paolini, C., De Francesco, R., Gallinari, P., et al. (2004) · Proceedings of the National Academy of Sciences

Histone Deacetylase Inhibitors ResearchEnzyme Structure and Function

Cited by 638

Unraveling the hidden catalytic activity of vertebrate class IIa histone deacetylases

Lahm, A., Paolini, C., Pallaoro, M., Nardi, M. C., Jones, P., Neddermann, P., Sambucini, S., Bottomley, M. J., Lo Surdo, P., Carfı́, A., et al. (2007) · Proceedings of the National Academy of Sciences

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 566

Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

Canettieri, G., Di Marcotullio, L., Greco, A., Coni, S., Antonucci, L., Infante, P., Pietrosanti, L., De Smaele, E., Ferretti, E., Miele, E., et al. (2010) · Nature Cell Biology

Hedgehog Signaling Pathway StudiesHistone Deacetylase Inhibitors Research

Cited by 322

Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8–substrate complex

Vannini, A., Volpari, C., Gallinari, P., Jones, P., Mattu, M., Carfí, A., De Francesco, R., Steinkühler, C., & Di Marco, S. (2007) · The EMBO Reports

Histone Deacetylase Inhibitors ResearchEnzyme Structure and Function

Cited by 256

PP2A Regulates HDAC4 Nuclear Import

Paroni, G., Cernotta, N., Dello Russo, C., Gallinari, P., Pallaoro, M., Foti, C., Talamo, F., Orsatti, L., Steinkühler, C., & Brancolini, C. (2008) · Molecular Biology of the Cell

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 126