HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

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The diverse functions of histone lysine methylation

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Histone Acetyltransferases

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

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Acetylation and deacetylation of non-histone proteins

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The Deacetylase HDAC6 Regulates Aggresome Formation and Cell Viability in Response to Misfolded Protein Stress

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The Sir2 Family of Protein Deacetylases

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HDAC6 Regulates Hsp90 Acetylation and Chaperone-Dependent Activation of Glucocorticoid Receptor

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Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

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Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

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Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

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Class II Histone Deacetylases Act as Signal-Responsive Repressors of Cardiac Hypertrophy

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Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer

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The many faces of histone lysine methylation

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Histone Deacetylase 4 Controls Chondrocyte Hypertrophy during Skeletogenesis

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Stat3 Dimerization Regulated by Reversible Acetylation of a Single Lysine Residue

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Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90

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Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

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Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A

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Untitled work

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In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation

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Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases

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A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

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Class II histone deacetylases: versatile regulators

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Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation

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Histone Deacetylases 5 and 9 Govern Responsiveness of the Heart to a Subset of Stress Signals and Play Redundant Roles in Heart Development

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The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

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The diverse functions of histone acetyltransferase complexes

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Apicidin: A novel antiprotozoal agent that inhibits parasite histone deacetylase

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Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer

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Histone deacetylase (HDAC) inhibitor activation of p21 WAF1 involves changes in promoter-associated proteins, including HDAC1

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Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications

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Protein Kinases C and D Mediate Agonist-Dependent Cardiac Hypertrophy through Nuclear Export of Histone Deacetylase 5

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CoREST is an integral component of the CoREST- human histone deacetylase complex

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Microarray Deacetylation Maps Determine Genome-Wide Functions for Yeast Histone Deacetylases

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The N-CoR-HDAC3 Nuclear Receptor Corepressor Complex Inhibits the JNK Pathway through the Integral Subunit GPS2

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Drug Insight: histone deacetylase inhibitors—development of the new targeted anticancer agent suberoylanilide hydroxamic acid

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Cloning and Characterization of a Novel Human Class I Histone Deacetylase That Functions as a Transcription Repressor

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Identification of a Signal-Responsive Nuclear Export Sequence in Class II Histone Deacetylases

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Genome-wide binding map of the histone deacetylase Rpd3 in yeast

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Requirement of Hos2 Histone Deacetylase for Gene Activity in Yeast

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Regulation of MEF2 by Histone Deacetylase 4- and SIRT1 Deacetylase-Mediated Lysine Modifications

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The Retinoblastoma-Histone Deacetylase 3 Complex Inhibits PPARγ and Adipocyte Differentiation

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Histone Deacetylase 1 Phosphorylation Promotes Enzymatic Activity and Complex Formation

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Functional Domains of Histone Deacetylase-3

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SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities

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