Arase, Hisashi

Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages

Haldar, M., Kohyama, M., So, A. Y.-L., KC, W., Wu, X., Briseño, C. G., Satpathy, A. T., Kretzer, N. M., Arase, H., Rajasekaran, N. S., et al. (2014) · Cell

Iron Metabolism and DisordersPhagocytosis and Immune Regulation

Cited by 431

LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration

Deng, M., Gui, X., Kim, J., Xie, L., Chen, W., Li, Z., He, L., Chen, Y., Chen, H., Luo, W., et al. (2018) · Nature

Immune Cell Function and InteractionCancer Immunotherapy and Biomarkers

Cited by 305

A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer’s disease

Zhao, P., Xu, Y., Jiang, L., Fan, X., Li, L., Li, X., Arase, H., Zhao, Y., Cao, W., Zheng, H., et al. (2022) · Science Translational Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 141

Functional and genetic diversity of leukocyte immunoglobulin-like receptor and implication for disease associations

Hirayasu, K., & Arase, H. (2015) · Journal of Human Genetics

Immune Cell Function and InteractionReproductive System and Pregnancy

Cited by 129

The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN

Soh, W. T., Liu, Y., Nakayama, E. E., Ono, C., Torii, S., Nakagami, H., Matsuura, Y., Shioda, T., & Arase, H. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 61

Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles

Kayama, H., Kohyama, M., Okuzaki, D., Motooka, D., Barman, S., Okumura, R., Muneta, M., Hoshino, K., Sasaki, I., Ise, W., et al. (2018) · Proceedings of the National Academy of Sciences

Inflammatory Bowel DiseaseImmune Response and Inflammation

Cited by 55

LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions

Zhao, P., Xu, Y., Jiang, L.-L., Fan, X., Ku, Z., Li, L., Liu, X., Deng, M., Arase, H., Zhu, J.-J., et al. (2022) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 54