Mannaerts, Inge

Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

Bonnardel, J., T’Jonck, W., Gaublomme, D., Browaeys, R., Scott, C. L., Martens, L., Vanneste, B., De Prijck, S., Nedospasov, S. A., Kremer, A., et al. (2019) · Immunity

Liver physiology and pathologyImmune cells in cancer

Cited by 631

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

Mannaerts, I., Leite, S. B., Verhulst, S., Claerhout, S., Eysackers, N., Thoen, L. F. R., Hoorens, A., Reynaert, H., Halder, G., & van Grunsven, L. A. (2015) · Journal of Hepatology

Liver physiology and pathologyHippo pathway signaling and YAP/TAZ

Cited by 410

A role for autophagy during hepatic stellate cell activation

Thoen, L. F. R., Guimarães, E. L. M., Dollé, L., Mannaerts, I., Najimi, M., Sokal, E., & van Grunsven, L. A. (2011) · Journal of Hepatology

Liver physiology and pathologyAutophagy in Disease and Therapy

Cited by 385

FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis

Verbeke, L., Mannaerts, I., Schierwagen, R., Govaere, O., Klein, S., Vander Elst, I., Windmolders, P., Farre, R., Wenes, M., Mazzone, M., et al. (2016) · Scientific Reports

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 236

Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro

Leite, S. B., Roosens, T., El Taghdouini, A., Mannaerts, I., Smout, A. J., Najimi, M., Sokal, E., Noor, F., Chesne, C., & van Grunsven, L. A. (2016) · Biomaterials

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 234

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

Coll, M., Perea, L., Boon, R., Leite, S. B., Vallverdú, J., Mannaerts, I., Smout, A., El Taghdouini, A., Blaya, D., Rodrigo-Torres, D., et al. (2018) · Cell Stem Cell

Liver physiology and pathologyPluripotent Stem Cells Research

Cited by 233

Initiation of hepatic stellate cell activation extends into chronic liver disease

De Smet, V., Eysackers, N., Merens, V., Kazemzadeh Dastjerd, M., Halder, G., Verhulst, S., Mannaerts, I., & van Grunsven, L. A. (2021) · Cell Death & Disease

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 78

Autophagy-Related Activation of Hepatic Stellate Cells Reduces Cellular miR-29a by Promoting Its Vesicular Secretion

Yu, X., Elfimova, N., Müller, M., Bachurski, D., Koitzsch, U., Drebber, U., Mahabir, E., Hansen, H. P., Friedman, S. L., Klein, S., et al. (2022) · Cellular and Molecular Gastroenterology and Hepatology

Liver physiology and pathologyMicroRNA in disease regulation

Cited by 27