DeFronzo, Ralph A.

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp

Matsuda, M., & DeFronzo, R. A. (1999) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsPancreatic function and diabetes

Cited by 5,621

The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM

DeFronzo, R. A. (1988) · Diabetes

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 2,456

Impaired Fasting Glucose and Impaired Glucose Tolerance

Nathan, D. M., Davidson, M. B., DeFronzo, R. A., Heine, R. J., Henry, R. R., Pratley, R., & Zinman, B. (2007) · Diabetes Care

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,396

Pathogenesis of type 2 diabetes mellitus

DeFronzo, R. A. (2004) · Medical Clinics of North America

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,342

Quantitation of Muscle Glycogen Synthesis in Normal Subjects and Subjects with Non-Insulin-Dependent Diabetes by13C Nuclear Magnetic Resonance Spectroscopy

Shulman, G. I., Rothman, D. L., Jue, T., Stein, P., DeFronzo, R. A., & Shulman, R. G. (1990) · New England Journal of Medicine

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,248

Effect of fatty acids on glucose production and utilization in man.

Ferrannini, E., Barrett, E. J., Bevilacqua, S., & DeFronzo, R. A. (1983) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,050

Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance.

Groop, L. C., Bonadonna, R. C., DelPrato, S., Ratheiser, K., Zyck, K., Ferrannini, E., & DeFronzo, R. A. (1989) · Journal of Clinical Investigation

Diabetes, Cardiovascular Risks, and LipoproteinsPancreatic function and diabetes

Cited by 812

Pioglitazone for Diabetes Prevention in Impaired Glucose Tolerance

DeFronzo, R. A., Tripathy, D., Schwenke, D. C., Banerji, M., Bray, G. A., Buchanan, T. A., Clement, S. C., Henry, R. R., Hodis, H. N., Kitabchi, A. E., et al. (2011) · New England Journal of Medicine

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 766

Pathogenesis of insulin resistance in skeletal muscle

Abdul-Ghani, M. A., & DeFronzo, R. A. (2010) · Journal of Biomedicine and Biotechnology

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 670

Role of the Adipocyte, Free Fatty Acids, and Ectopic Fat in Pathogenesis of Type 2 Diabetes Mellitus: Peroxisomal Proliferator-Activated Receptor Agonists Provide a Rational Therapeutic Approach

Bays, H., Mandarino, L., & DeFronzo, R. A. (2004) · The Journal of Clinical Endocrinology & Metabolism

Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 664

Metformin-associated lactic acidosis: current perspectives on causes and risk

DeFronzo, R., Fleming, G. A., Chen, K., & Bicsak, T. A. (2016) · Metabolism

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 658

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm - 2020 executive summary

Garber, A. J., Handelsman, Y., Grunberger, G., Einhorn, D., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bush, M. A., DeFronzo, R. A., Garber, J. R., et al. (2020) · Endocrine Practice

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 598

Epinephrine-induced insulin resistance in man

Deibert, D. C., & Defronzo, R. A. (1980) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 557

Insulin Resistance and Atherosclerosis: Implications for Insulin-Sensitizing Agents

Di Pino, A., & DeFronzo, R. A. (2019) · Endocrine Reviews

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 535

Fasting hyperglycemia in non-insulin-dependent diabetes mellitus: contributions of excessive hepatic glucose production and impaired tissue glucose uptake

DeFronzo, R. A., Ferrannini, E., & Simonson, D. C. (1989) · Metabolism

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and Research

Cited by 515

American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.

Blonde, L., Umpierrez, G. E., Reddy, S. S., McGill, J. B., Berga, S. L., Bush, M., Chandrasekaran, S., DeFronzo, R. A., Einhorn, D., Galindo, R. J., et al. (2022) · Endocrine Practice

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 507

The Disposal of an Oral Glucose Load in Healthy Subjects: A Quantitative Study

Ferrannini, E., Bjorkman, O., Reichard, G. A., Pilo, A., Olsson, M., Wahren, J., & DeFronzo, R. A. (1985) · Diabetes

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 439

Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm – 2017 executive summary

Garber, A. J., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bloomgarden, Z. T., Bush, M. A., Dagogo-Jack, S., DeFronzo, R. A., Einhorn, D., Fonseca, V. A., et al. (2017) · Endocrine Practice

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 435

Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects

DEFRONZO, R. A., BARZILAI, N., & SIMONSON, D. C. (1991) · The Journal of Clinical Endocrinology & Metabolism

Diabetes Treatment and ManagementMetabolism, Diabetes, and Cancer

Cited by 408

Identification of Individuals With Insulin Resistance Using Routine Clinical Measurements

Stern, S. E., Williams, K., Ferrannini, E., DeFronzo, R. A., Bogardus, C., & Stern, M. P. (2005) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

Cited by 384

Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: A randomized, cross-over study

DeFronzo, R. A., Okerson, T., Viswanathan, P., Guan, X., Holcombe, J. H., & MacConell, L. (2008) · Current Medical Research and Opinion

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 373

American Association of Clinical Endocrinologists and American College of Endocrinology Position Statement on the Association of SGLT-2 Inhibitors and Diabetic Ketoacidosis

Handelsman, Y., Henry, R. R., Bloomgarden, Z. T., Dagogo-Jack, S., DeFronzo, R. A., Einhorn, D., Ferrannini, E., Fonseca, V. A., Garber, A. J., Grunberger, G., et al. (2016) · Endocrine Practice

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 358

What is the best predictor of future type 2 diabetes

Abdul-Ghani, M. A., Williams, K., DeFronzo, R. A., & Stern, M. (2007) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsPancreatic function and diabetes

Cited by 355

Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study

Gastaldelli, A., Ferrannini, E., Miyazaki, Y., Matsuda, M., & DeFronzo, R. A. (2004) · Diabetologia

Pancreatic function and diabetesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 338