Chen, Jie

Phosphatidic Acid-Mediated Mitogenic Activation of mTOR Signaling

Fang, Y., Vilella-Bach, M., Bachmann, R., Flanigan, A., & Chen, J. (2001) · Science

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

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Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue.

Chen, J., Zheng, X. F., Brown, E. J., & Schreiber, S. L. (1995) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease

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Chapter 21 Interleukin‐6 and Insulin Resistance

Kim, J., Bachmann, R. A., & Chen, J. (2009) · Vitamins & Hormones

Adipokines, Inflammation, and Metabolic DiseasesCytokine Signaling Pathways and Interactions

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Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice

Fang, Y., Westbrook, R., Hill, C., Boparai, R. K., Arum, O., Spong, A., Wang, F., Javors, M. A., Chen, J., Sun, L. Y., et al. (2013) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsPI3K/AKT/mTOR signaling in cancer

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The FKBP12-Rapamycin-binding Domain Is Required for FKBP12-Rapamycin-associated Protein Kinase Activity and G1 Progression

Vilella-Bach, M., Nuzzi, P., Fang, Y., & Chen, J. (1999) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease

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Regulation of Interleukin-6-induced Hepatic Insulin Resistance by Mammalian Target of Rapamycin through the STAT3-SOCS3 Pathway

Kim, J.-H., Kim, J. E., Liu, H.-Y., Cao, W., & Chen, J. (2008) · Journal of Biological Chemistry

Cytokine Signaling Pathways and InteractionsAdipokines, Inflammation, and Metabolic Diseases

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(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest

Hung, D. T., Chen, J., & Schreiber, S. L. (1996) · Chemistry & Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

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Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation

Kim, J.-H., Yoon, M.-S., & Chen, J. (2009) · Journal of Biological Chemistry

Cytokine Signaling Pathways and InteractionsMetabolism, Diabetes, and Cancer

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PLD regulates myoblast differentiation through the mTOR-IGF2 pathway

Yoon, M.-S., & Chen, J. (2008) · Journal of Cell Science

Muscle Physiology and DisordersPI3K/AKT/mTOR signaling in cancer

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Lack of muscle mTOR kinase activity causes early onset myopathy and compromises whole‐body homeostasis

Zhang, Q., Duplany, A., Moncollin, V., Mouradian, S., Goillot, E., Mazelin, L., Gauthier, K., Streichenberger, N., Angleraux, C., Chen, J., et al. (2019) · Journal of Cachexia, Sarcopenia and Muscle

Muscle Physiology and DisordersPI3K/AKT/mTOR signaling in cancer

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