Chen, Yang

Tumor-repopulating cells induce PD-1 expression in CD8(+) T cells by transferring kynurenine and AhR activation

Liu, Y., Liang, X., Dong, W., Fang, Y., Lv, J., Zhang, T., Fiskesund, R., Xie, J., Liu, J., Yin, X., et al. (2018) · Cancer Cell

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 535

MFN1 structures reveal nucleotide-triggered dimerization critical for mitochondrial fusion

Cao, Y.-L., Meng, S., Chen, Y., Feng, J.-X., Gu, D.-D., Yu, B., Li, Y.-J., Yang, J.-Y., Liao, S., Chan, D. C., et al. (2017) · Nature

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 326

Orally administered CLA ameliorates DSS-induced colitis in mice via intestinal barrier improvement, oxidative stress reduction, and inflammatory cytokine and gut microbiota modulation

Chen, Y., Yang, B., Ross, R. P., Jin, Y., Stanton, C., Zhao, J., Zhang, H., & Chen, W. (2019) · Journal of Agricultural and Food Chemistry

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 185

Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer

Tong, X., Patel, A. S., Kim, E., Li, H., Chen, Y., Li, S., Liu, S., Dilly, J., Kapner, K. S., Zhang, N., et al. (2024) · Cancer Cell

Lung Cancer Treatments and MutationsCancer Cells and Metastasis

Cited by 142

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control

Yang, J.-Y., Deng, X.-Y., Li, Y.-S., Ma, X.-C., Feng, J.-X., Yu, B., Chen, Y., Luo, Y.-L., Wang, X., Chen, M.-L., et al. (2018) · Nature Communications

RNA and protein synthesis mechanismsRNA Research and Splicing

Cited by 124

Revolutionizing GPCR–ligand predictions: DeepGPCR with experimental validation for high-precision drug discovery

Zhang, H., Fan, H., Wang, J., Hou, T., Saravanan, K. M., Xia, W., Kan, H. W., Li, J., Zhang, J. Z. H., Liang, X., et al. (2024) · Briefings in Bioinformatics

Computational Drug Discovery MethodsReceptor Mechanisms and Signaling

Cited by 25