Wang, Lili

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Gao, G.-P., Alvira, M. R., Wang, L., Calcedo, R., Johnston, J., & Wilson, J. M. (2002) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 1,520

Treatment of Leber Congenital Amaurosis Due to RPE65 Mutations by Ocular Subretinal Injection of Adeno-Associated Virus Gene Vector: Short-Term Results of a Phase I Trial

Hauswirth, W. W., Aleman, T. S., Kaushal, S., Cideciyan, A. V., Schwartz, S. B., Wang, L., Conlon, T. J., Boye, S. L., Flotte, T. R., Byrne, B. J., et al. (2008) · Human Gene Therapy

Retinal Development and DisordersVirus-based gene therapy research

Cited by 954

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo

Noble, W., Planel, E., Zehr, C., Olm, V., Meyerson, J., Suleman, F., Gaynor, K., Wang, L., LaFrancois, J., Feinstein, B., et al. (2005) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 709

A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice

Yang, Y., Wang, L., Bell, P., McMenamin, D., He, Z., White, J., Yu, H., Xu, C., Morizono, H., Musunuru, K., et al. (2016) · Nature Biotechnology

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 556

ACVR1 R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A

Hatsell, S. J., Idone, V., Wolken, D. M. A., Huang, L., Kim, H. J., Wang, L., Wen, X., Nannuru, K. C., Jimenez, J., Xie, L., et al. (2015) · Science Translational Medicine

Heterotopic Ossification and Related ConditionsBone Tumor Diagnosis and Treatments

Cited by 446

Adeno-Associated Virus Antibody Profiles in Newborns, Children, and Adolescents

Calcedo, R., Morizono, H., Wang, L., McCarter, R., He, J., Jones, D., Batshaw, M. L., & Wilson, J. M. (2011) · Clinical and Vaccine Immunology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 345

Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy

Brantly, M. L., Chulay, J. D., Wang, L., Mueller, C., Humphries, M., Spencer, L. T., Rouhani, F., Conlon, T. J., Calcedo, R., Betts, M. R., et al. (2009) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 327

Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey

Vandenberghe, L. H., Bell, P., Maguire, A. M., Cearley, C. N., Xiao, R., Calcedo, R., Wang, L., Castle, M. J., Maguire, A. C., Grant, R., et al. (2011) · Science Translational Medicine

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 242

Impact of Pre-Existing Immunity on Gene Transfer to Nonhuman Primate Liver with Adeno-Associated Virus 8 Vectors

Wang, L., Calcedo, R., Bell, P., Lin, J., Grant, R. L., Siegel, D. L., & Wilson, J. M. (2011) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 212

Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid

Vandenberghe, L. H., Wang, L., Somanathan, S., Zhi, Y., Figueredo, J., Calcedo, R., Sanmiguel, J., Desai, R. A., Chen, C. S., Johnston, J., et al. (2006) · Nature Medicine

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 208

Sustained correction of disease in naive and AAV2-pretreated hemophilia b dogs: AAV2/8-mediated, liver-directed gene therapy

Wang, L., Calcedo, R., Nichols, T. C., Bellinger, D. A., Dillow, A., Verma, I. M., & Wilson, J. M. (2005) · Blood

Virus-based gene therapy researchHemophilia Treatment and Research

Cited by 173

Interplay between Cyclin-Dependent Kinase 5 and Glycogen Synthase Kinase 3β Mediated by Neuregulin Signaling Leads to Differential Effects on Tau Phosphorylation and Amyloid Precursor Protein Processing

Wen, Y., Planel, E., Herman, M., Figueroa, H. Y., Wang, L., Liu, L., Lau, L.-F., Yu, W. H., & Duff, K. E. (2008) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsProtein Kinase Regulation and GTPase Signaling

Cited by 145

The Pleiotropic Effects of Natural AAV Infections on Liver-directed Gene Transfer in Macaques

Wang, L., Calcedo, R., Wang, H., Bell, P., Grant, R., Vandenberghe, L. H., Sanmiguel, J., Morizono, H., Batshaw, M. L., & Wilson, J. M. (2010) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 130

Cross-presentation of adeno-associated virus serotype 2 capsids activates cytotoxic T cells but does not render hepatocytes effective cytolytic targets

Wang, L., Figueredo, J., Calcedo, R., Lin, J., & Wilson, J. M. (2007) · Human Gene Therapy

Virus-based gene therapy researchImmunotherapy and Immune Responses

Cited by 113

Myocardial gene delivery using molecular cardiac surgery with recombinant adeno-associated virus vectors in vivo

White, J. D., Thesier, D. M., Swain, J. B. D., Katz, M. G., Tomasulo, C., Henderson, A., Wang, L., Yarnall, C., Fargnoli, A., Sumaroka, M., et al. (2011) · Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 73

Effects of self-complementarity, codon optimization, transgene, and dose on liver transduction with AAV8

Bell, P., Wang, L., Chen, S.-J., Yu, H., Zhu, Y., Nayal, M., He, Z., White, J., Lebel-Hagan, D., & Wilson, J. M. (2016) · Human Gene Therapy Methods

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 26

TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3

Chang, X., Wang, L., Wang, Z., Wu, S., Zhu, X., Hu, S., Wang, Y., Yu, J., & Chen, G. (2017) · Scientific Reports

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 13