Chen, Xiaochun

TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

Zhao, Y., Wu, X., Li, X., Jiang, L.-L., Gui, X., Liu, Y., Sun, Y., Zhu, B., Piña-Crespo, J. C., Zhang, M., et al. (2018) · Neuron

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 763

Longevity of centenarians is reflected by the gut microbiome with youth-associated signatures

Pang, S., Chen, X., Lu, Z., Meng, L., Huang, Y., Yu, X., Huang, L., Ye, P., Chen, X., Liang, J., et al. (2023) · Nature Aging

Gut microbiota and healthGenetics, Aging, and Longevity in Model Organisms

Cited by 173

TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration

Zhong, L., Sheng, X., Wang, W., Li, Y., Zhuo, R., Wang, K., Zhang, L., Hu, D.-D., Hong, Y., Chen, L., et al. (2023) · Immunity

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 168

Myelin changes at the early stage of 5XFAD mice

Gu, L., Wu, D., Tang, X., Qi, X., Li, X., Bai, F., Chen, X., Ren, Q., & Zhang, Z. (2018) · Brain Research Bulletin

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 87

APOE4 genotype exacerbates the depression-like behavior of mice during aging through ATP decline

Fang, W., Xiao, N., Zeng, G., Bi, D., Dai, X., Mi, X., Ye, Q., Chen, X., & Zhang, J. (2021) · Translational Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 42

APOE4 Induces Site-Specific Tau Phosphorylation Through Calpain-CDK5 Signaling Pathway in EFAD-Tg Mice

Zhou, M., Huang, T., Collins, N., Zhang, J., Shen, H., Dai, X., Xiao, N., Wu, X., Wei, Z., York, J., et al. (2016) · Current Alzheimer Research

Alzheimer's disease research and treatmentsCalpain Protease Function and Regulation

Cited by 40

APOE ε4 allele accelerates age-related multi-cognitive decline and white matter damage in non-demented elderly

Sun, J., Zhu, Z., Chen, K., Wei, D., Li, X., Li, H., Zhang, J., Chen, X., Chen, Y., & Zhang, Z. (2020) · Aging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 16