Wang, Ming-Wei

Structure and dynamics of the active human parathyroid hormone receptor-1

Zhao, L.-H., Ma, S., Sutkeviciute, I., Shen, D.-D., Zhou, X. E., de Waal, P. W., Li, C.-Y., Kang, Y., Clark, L. J., Jean-Alphonse, F. G., et al. (2019) · Science

Receptor Mechanisms and SignalingProtein Structure and Dynamics

Cited by 256

Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

Song, G., Yang, D., Wang, Y., de Graaf, C., Zhou, Q., Jiang, S., Liu, K., Cai, X., Dai, A., Lin, G., et al. (2017) · Nature

Receptor Mechanisms and SignalingDiabetes Treatment and Management

Cited by 241

Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors

Zhao, F., Zhou, Q., Cong, Z., Hang, K., Zou, X., Zhang, C., Chen, Y., Dai, A., Liang, A., Ming, Q., et al. (2022) · Nature Communications

Receptor Mechanisms and SignalingDiabetes Treatment and Management

Cited by 149

DeepCPI: A Deep Learning-Based Framework for Large-Scale in Silico Drug Screening

Wan, F., Zhu, Y., Hu, H., Dai, A., Cai, X., Chen, L., Gong, H., Xia, T., Yang, D., Wang, M.-W., et al. (2019) · Genomics, Proteomics & Bioinformatics

Computational Drug Discovery MethodsMachine Learning in Bioinformatics

Cited by 92

Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor

Lu, Y., Qin, S., Zhang, B., Dai, A., Cai, X., Ma, M., Gao, Z.-G., Yang, D., Stevens, R. C., Jacobson, K. A., et al. (2019) · Analytical Chemistry

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 39

Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide

Li, W., Zhou, Q., Cong, Z., Yuan, Q., Li, W., Zhao, F., Xu, H. E., Zhao, L.-H., Yang, D., & Wang, M.-W. (2024) · Cell Discovery

Receptor Mechanisms and SignalingDiabetes Treatment and Management

Cited by 32